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Open Access
Peer-reviewed
Research Article
In vivo efficacy of the boron-pleuromutilin AN11251 against Wolbachia of the rodent filarial nematode Litomosoides sigmodontis
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Alexandra Ehrens ,
Roles Formal analysis, Methodology, Writing – original draft, Writing – review & editing
¶‡ AE and CSL share first authorship on this work. AH and MPH share last authorship on this work.
Affiliation Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany
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Christopher S. Lunde ,
Roles Conceptualization, Project administration, Writing – original draft, Writing – review & editing
¶‡ AE and CSL share first authorship on this work. AH and MPH share last authorship on this work.
Affiliation Anacor Pharmaceuticals, Palo Alto, California, United States of America
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Robert T. Jacobs,
Roles Conceptualization, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
Affiliation Anacor Pharmaceuticals, Palo Alto, California, United States of America
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Dominique Struever,
Roles Formal analysis, Methodology
Affiliation Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany
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Marianne Koschel,
Roles Formal analysis, Methodology
Affiliation Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany
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Stefan J. Frohberger,
Roles Methodology
Affiliation Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany
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Franziska Lenz,
Roles Methodology
Affiliation Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany
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Martina Fendler,
Roles Methodology
Affiliation Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany
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Joseph D. Turner,
Roles Conceptualization, Writing – review & editing
Affiliation Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
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Stephen A. Ward,
Roles Conceptualization, Writing – review & editing
Affiliation Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
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Mark J. Taylor,
Roles Conceptualization, Writing – review & editing
Affiliation Centre for Drugs and Diagnostics, Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
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Yvonne R. Freund,
Roles Conceptualization, Project administration
Affiliation Anacor Pharmaceuticals, Palo Alto, California, United States of America
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Rianna Stefanakis,
Roles Conceptualization, Project administration, Resources
Affiliation Anacor Pharmaceuticals, Palo Alto, California, United States of America
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Eric Easom,
Roles Conceptualization, Resources
Affiliation Anacor Pharmaceuticals, Palo Alto, California, United States of America
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Xianfeng Li,
Roles Conceptualization, Resources
Affiliation Anacor Pharmaceuticals, Palo Alto, California, United States of America
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Jacob J. Plattner,
Roles Conceptualization, Project administration, Resources
Affiliation Anacor Pharmaceuticals, Palo Alto, California, United States of America
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Achim Hoerauf ,
Roles Conceptualization, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
¶‡ AE and CSL share first authorship on this work. AH and MPH share last authorship on this work.
Affiliations Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany, German Center for Infection Research (DZIF), partner site Bonn-Cologne, Bonn, Germany
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Marc P. Hübner
Roles Conceptualization, Formal analysis, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: huebner@uni-bonn.de
¶‡ AE and CSL share first authorship on this work. AH and MPH share last authorship on this work.
Affiliation Institute for Medical Microbiology, Immunology and Parasitology, University Hospital Bonn, Bonn, Germany
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In vivo efficacy of the boron-pleuromutilin AN11251 against Wolbachia of the rodent filarial nematode Litomosoides sigmodontis
- Alexandra Ehrens,
- Christopher S. Lunde,
- Robert T. Jacobs,
- Dominique Struever,
- Marianne Koschel,
- Stefan J. Frohberger,
- Franziska Lenz,
- Martina Fendler,
- Joseph D. Turner,
- Stephen A. Ward
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- Published: January 27, 2020
- https://doi.org/10.1371/journal.pntd.0007957