Treatment responses to Azithromycin and Ciprofloxacin in uncomplicated Salmonella Typhi infection: A comparison of Clinical and Microbiological Data from a Controlled Human Infection Model

• Celina Jin ,

  Contributed equally to this work with: Celina Jin, Malick M. Gibani

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom

  http://orcid.org/0000-0002-7614-8787

  ⨯
• Malick M. Gibani ,

  Contributed equally to this work with: Celina Jin, Malick M. Gibani

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Malick.Gibani@paediatrics.ox.ac.uk

  Affiliations Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom, Department of Infectious Diseases, Imperial College London, London, United Kingdom

  http://orcid.org/0000-0003-1781-0053

  ⨯
• Shaun H. Pennington,

  Roles Data curation, Formal analysis, Methodology, Visualization, Writing – review & editing

  Affiliation Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

  http://orcid.org/0000-0002-7160-6275

  ⨯
• Xinxue Liu,

  Roles Data curation, Formal analysis, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom

  http://orcid.org/0000-0003-1107-0365

  ⨯
• Alison Ardrey,

  Roles Formal analysis, Methodology, Validation

  Affiliation Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

  ⨯
• Ghaith Aljayyoussi,

  Roles Formal analysis, Methodology, Validation

  Affiliation Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

  ⨯
• Maria Moore,

  Roles Data curation, Investigation, Project administration, Writing – review & editing

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom

  ⨯
• Brian Angus,

  Roles Conceptualization, Investigation, Supervision, Writing – review & editing

  Affiliation Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

  http://orcid.org/0000-0003-3598-7784

  ⨯
• Christopher M. Parry,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliations Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool, United Kingdom, Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom, School of Tropical Medicine and Global Health, Nagsaki University, Nagasaki, Japan

  ⨯
• Giancarlo A. Biagini,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

  ⨯
• Nicholas A. Feasey ,

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work.

  Affiliations Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom, Malawi Liverpool Wellcome Trust Clinical research Programme, Blantyre, Malawi

  http://orcid.org/0000-0003-4041-1405

  ⨯
• Andrew J. Pollard

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work.

  Affiliation Oxford Vaccine Group, Department of Paediatrics, University of Oxford, and NIHR Oxford Biomedical Research Centre, Oxford, United Kingdom

  http://orcid.org/0000-0001-7361-719X

  ⨯