Characterization of Entamoeba histolytica adenosine 5′-phosphosulfate (APS) kinase; validation as a target and provision of leads for the development of new drugs against amoebiasis

• Fumika Mi-ichi ,

  Contributed equally to this work with: Fumika Mi-ichi, Takeshi Ishikawa

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: fumika@cc.saga-u.ac.jp

  Affiliation Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan

  http://orcid.org/0000-0001-7042-2266

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• Takeshi Ishikawa ,

  Contributed equally to this work with: Fumika Mi-ichi, Takeshi Ishikawa

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Current address: Department of Chemistry, Biotechnology, and Chemical Engineering, Graduate School of Science and Engineering, Kagoshima University, Korimoto, Kagoshima Japan

  Affiliation Department of Molecular Microbiology and Immunology, Graduate School of Biomedical Sciences, Nagasaki University, Sakamoto, Nagasaki, Japan

  http://orcid.org/0000-0002-3187-1381

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• Vo Kha Tam,

  Roles Formal analysis, Investigation

  Affiliation Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan

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• Sharmina Deloer,

  Roles Investigation

  Affiliation Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan

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• Shinjiro Hamano,

  Roles Funding acquisition, Investigation, Writing – review & editing

  Affiliation Department of Parasitology, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Sakamoto, Nagasaki, Japan

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• Tsuyoshi Hamada,

  Roles Formal analysis, Investigation

  Affiliation Nagasaki Advanced Computing Center, Nagasaki University, Bunkyo-machi, Nagasaki, Japan

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• Hiroki Yoshida

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Writing – review & editing

  Affiliation Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan

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