The E3 ligase TRIM56 is a host restriction factor of Zika virus and depends on its RNA-binding activity but not miRNA regulation, for antiviral function

• Darong Yang,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, United States of America, Children’s Foundation Research Institute at Le Bonheur Children’s Hospital, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, United States of America

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• Nan L. Li,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, United States of America

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• Dahai Wei,

  Roles Resources

  Current address: Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China;

  Affiliation Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, United States of America

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• Baoming Liu,

  Roles Investigation

  Current address: Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America

  Affiliation Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, United States of America

  http://orcid.org/0000-0003-2204-9828

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• Fang Guo,

  Roles Resources

  Affiliation Baruch S. Blumberg Institute, Doylestown, PA, United States of America

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• Husni Elbahesh,

  Roles Data curation, Investigation

  Affiliation Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, United States of America

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• Yunzhi Zhang,

  Roles Investigation

  Affiliations Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, United States of America, Department of Infectious Diseases, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Zhi Zhou,

  Roles Supervision

  Affiliation Department of Infectious Diseases, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Guo-Yun Chen,

  Roles Resources, Supervision

  Affiliation Children’s Foundation Research Institute at Le Bonheur Children’s Hospital, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, United States of America

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• Kui Li

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: kli1@uthsc.edu.

  Affiliation Department of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, United States of America

  http://orcid.org/0000-0002-2413-6020

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