Genomic instability at the locus of sterol C24-methyltransferase promotes amphotericin B resistance in Leishmania parasites

• Andrew W. Pountain,

  Roles Conceptualization, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliations Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom, Department of Microbiology and Molecular Genetics, University of Texas Health Science Center at Houston, Houston, Texas, United States of America

  http://orcid.org/0000-0001-9651-5145

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• Stefan K. Weidt,

  Roles Formal analysis, Investigation

  Affiliation Glasgow Polyomics, College of Medical, Veterinary & Life Sciences, University of Glasgow, Garscube Estate, Bearsden, Glasgow, United Kingdom

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• Clément Regnault,

  Roles Investigation

  Affiliation Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom

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• Paul A. Bates,

  Roles Resources, Writing – review & editing

  Affiliation Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, United Kingdom

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• Anne M. Donachie,

  Roles Investigation

  Affiliation Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom

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• Nicholas J. Dickens,

  Roles Conceptualization, Supervision

  Affiliation Marine Biomedical & Biotechnology Research Program, Florida Atlantic University Harbor Branch Oceanographic Institute, Fort Pierce, Florida, United States of America

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• Michael P. Barrett

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Michael.Barrett@glasgow.ac.uk

  Affiliation Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom

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