Identification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screening

• Lorenzo Turcano,

  Roles Data curation, Investigation, Methodology, Writing – original draft

  Affiliation IRBM Science Park S.p.A. Via Pontina Km 30,600–00071 Pomezia (RM), Italy

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• Esther Torrente,

  Roles Data curation, Investigation

  Affiliation IRBM Science Park S.p.A. Via Pontina Km 30,600–00071 Pomezia (RM), Italy

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• Antonino Missineo,

  Roles Data curation, Investigation

  Affiliation IRBM Science Park S.p.A. Via Pontina Km 30,600–00071 Pomezia (RM), Italy

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• Matteo Andreini,

  Roles Data curation, Investigation, Methodology

  Affiliation IRBM Science Park S.p.A. Via Pontina Km 30,600–00071 Pomezia (RM), Italy

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• Marina Gramiccia,

  Roles Data curation, Investigation

  Affiliation Dipartimento di Malattie Infettive,—Istituto Superiore di Sanità Viale Regina Elena, Roma, Italy

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• Trentina Di Muccio,

  Roles Data curation, Investigation

  Affiliation Dipartimento di Malattie Infettive,—Istituto Superiore di Sanità Viale Regina Elena, Roma, Italy

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• Ilaria Genovese,

  Roles Data curation, Investigation

  Affiliation Dipartimento di Scienze Biochimiche, “Sapienza” Università di Roma P.le A. Moro, Roma, Italy

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• Annarita Fiorillo,

  Roles Data curation, Investigation

  Affiliation Dipartimento di Scienze Biochimiche, “Sapienza” Università di Roma P.le A. Moro, Roma, Italy

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• Steven Harper,

  Roles Data curation, Investigation, Writing – original draft, Writing – review & editing

  Affiliation IRBM Science Park S.p.A. Via Pontina Km 30,600–00071 Pomezia (RM), Italy

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• Alberto Bresciani,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation IRBM Science Park S.p.A. Via Pontina Km 30,600–00071 Pomezia (RM), Italy

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• Gianni Colotti ,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Writing – original draft, Writing – review & editing

  * E-mail: gianni.colotti@uniroma1.it (GC); andrea.ilari@uniroma1.it (AI)

  Affiliation Istituto di Biologia e Patologia Molecolari–CNR, and Dipartimento di Scienze Biochimiche, “Sapienza” Università di Roma P.le A. Moro, Roma, Italy

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• Andrea Ilari

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: gianni.colotti@uniroma1.it (GC); andrea.ilari@uniroma1.it (AI)

  Affiliation Istituto di Biologia e Patologia Molecolari–CNR, and Dipartimento di Scienze Biochimiche, “Sapienza” Università di Roma P.le A. Moro, Roma, Italy

  http://orcid.org/0000-0002-7754-399X

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