Pharmacological characterization of crotamine effects on mice hind limb paralysis employing both ex vivo and in vivo assays: Insights into the involvement of voltage-gated ion channels in the crotamine action on skeletal muscles

• Sunamita de Carvalho Lima,

  Roles Data curation, Formal analysis, Writing – original draft

  Affiliation Departamento de Farmacologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Lucas de Carvalho Porta,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  Affiliation Departamento de Farmacologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Álvaro da Costa Lima,

  Roles Data curation, Formal analysis

  Affiliation Departamento de Farmacologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Joana D’Arc Campeiro,

  Roles Formal analysis, Visualization, Writing – original draft

  Affiliation Departamento de Farmacologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Ywlliane Meurer,

  Roles Data curation, Formal analysis, Methodology

  Affiliation Departamento de Fisiologia, Universidade Federal do Rio Grande do Norte (UFRN), Natal, Brazil

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• Nathália Bernardes Teixeira,

  Roles Data curation, Methodology

  Affiliation Laboratório Especial de Dor e Sinalização, Instituto Butantan, São Paulo, Brazil

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• Thiago Duarte,

  Roles Conceptualization, Methodology, Supervision

  Affiliation Departamento de Farmacologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Eduardo Brandt Oliveira,

  Roles Conceptualization, Formal analysis, Supervision, Writing – review & editing

  Affiliation Departamento de Bioquímica e Imunologia, Universidade de São Paulo (USP-RP), Ribeirão Preto, Brazil

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• Gisele Picolo,

  Roles Methodology, Supervision

  Affiliation Laboratório Especial de Dor e Sinalização, Instituto Butantan, São Paulo, Brazil

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• Rosely Oliveira Godinho,

  Roles Conceptualization, Data curation, Formal analysis, Supervision, Writing – review & editing

  Affiliation Departamento de Farmacologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Regina Helena Silva,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Departamento de Farmacologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

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• Mirian Akemi Furuie Hayashi

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: mhayashi@unifesp.br, mirianhayashi@yahoo.com

  Affiliation Departamento de Farmacologia, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil

  http://orcid.org/0000-0001-6437-4923

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