2,4-Diaminothieno[3,2-d]pyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm

• Frederick A. Partridge ,

  Contributed equally to this work with: Frederick A. Partridge, Ruth Forman, Nicky J. Willis, Carole J. R. Bataille

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Centre for Respiratory Biology, UCL Respiratory, Division of Medicine, University College London, London, United Kingdom

  http://orcid.org/0000-0001-6236-4297

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• Ruth Forman ,

  Contributed equally to this work with: Frederick A. Partridge, Ruth Forman, Nicky J. Willis, Carole J. R. Bataille

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

  ⨯
• Nicky J. Willis ,

  Contributed equally to this work with: Frederick A. Partridge, Ruth Forman, Nicky J. Willis, Carole J. R. Bataille

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom

  ⨯
• Carole J. R. Bataille ,

  Contributed equally to this work with: Frederick A. Partridge, Ruth Forman, Nicky J. Willis, Carole J. R. Bataille

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom

  ⨯
• Emma A. Murphy,

  Roles Conceptualization, Formal analysis, Investigation, Methodology

  Current address: Liverpool School of Tropical Medicine, Liverpool, United Kingdom

  Affiliation Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

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• Anwen E. Brown,

  Roles Investigation, Methodology

  Affiliation Centre for Respiratory Biology, UCL Respiratory, Division of Medicine, University College London, London, United Kingdom

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• Narinder Heyer-Chauhan,

  Roles Investigation, Methodology

  Affiliation Centre for Respiratory Biology, UCL Respiratory, Division of Medicine, University College London, London, United Kingdom

  ⨯
• Bruno Marinič,

  Roles Investigation

  Affiliation Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom

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• Daniel J. C. Sowood,

  Roles Investigation

  Affiliation Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom

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• Graham M. Wynne,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom

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• Kathryn J. Else ,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: d.sattelle@ucl.ac.uk (DBS); kathryn.else@manchester.ac.uk (KJE); angela.russell@chem.ox.ac.uk (AJR)

  Affiliation Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

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• Angela J. Russell ,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

  * E-mail: d.sattelle@ucl.ac.uk (DBS); kathryn.else@manchester.ac.uk (KJE); angela.russell@chem.ox.ac.uk (AJR)

  Affiliations Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom, Department of Pharmacology, University of Oxford, Oxford, United Kingdom

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• David B. Sattelle

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: d.sattelle@ucl.ac.uk (DBS); kathryn.else@manchester.ac.uk (KJE); angela.russell@chem.ox.ac.uk (AJR)

  Affiliation Centre for Respiratory Biology, UCL Respiratory, Division of Medicine, University College London, London, United Kingdom

  http://orcid.org/0000-0003-0705-5242

  ⨯