Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei

• Pieter C. Steketee,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Current address: The Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, United Kingdom

  Affiliation Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

  http://orcid.org/0000-0003-3677-5898

  ⨯
• Isabel M. Vincent,

  Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

  ⨯
• Fiona Achcar,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology

  Affiliation Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

  ⨯
• Federica Giordani,

  Roles Conceptualization, Investigation, Methodology

  Affiliation Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

  http://orcid.org/0000-0001-9964-281X

  ⨯
• Dong-Hyun Kim,

  Roles Data curation, Formal analysis, Methodology, Software

  Affiliation Centre for Analytical Bioscience, Division of Molecular and Cellular Sciences, School of Pharmacy, The University of Nottingham, Nottingham, United Kingdom

  ⨯
• Darren J. Creek,

  Roles Conceptualization, Methodology, Software

  Affiliation Department of Biochemistry and Molecular Biology, Drug Delivery Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia

  http://orcid.org/0000-0001-7497-7082

  ⨯
• Yvonne Freund,

  Roles Resources, Writing – review & editing

  Affiliation Anacor Pharmaceuticals, Inc., Palo Alto, California, United States of America

  ⨯
• Robert Jacobs,

  Roles Resources, Writing – review & editing

  Affiliation Anacor Pharmaceuticals, Inc., Palo Alto, California, United States of America

  ⨯
• Kevin Rattigan,

  Roles Investigation, Methodology

  Affiliation Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

  http://orcid.org/0000-0003-0212-0017

  ⨯
• David Horn,

  Roles Writing – review & editing

  Affiliation Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom

  ⨯
• Mark C. Field,

  Roles Writing – review & editing

  Affiliation Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom

  ⨯
• Annette MacLeod,

  Roles Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – review & editing

  Affiliation Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

  ⨯
• Michael P. Barrett

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

  * E-mail: michael.barrett@glasgow.ac.uk

  Affiliation Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom

  ⨯