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Open Access
Peer-reviewed
Research Article
Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models
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Hanna T. Sjoberg,
Roles Formal analysis, Investigation, Methodology, Writing – original draft
Affiliation Department of Parasitology and Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom
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Nicolas Pionnier,
Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing
Affiliation Department of Parasitology and Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom
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Ghaith Aljayyoussi,
Roles Formal analysis, Methodology, Writing – original draft
Affiliation Department of Parasitology and Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom
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Haelly M. Metuge,
Roles Formal analysis, Investigation, Methodology
Affiliations Research Foundation in Tropical Medicine and the Environment, Buea, Cameroon, Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon
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Abdel J. Njouendou,
Roles Investigation
Affiliations Research Foundation in Tropical Medicine and the Environment, Buea, Cameroon, Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon
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Valerine C. Chunda,
Roles Investigation
Affiliations Research Foundation in Tropical Medicine and the Environment, Buea, Cameroon, Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon
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Fanny F. Fombad,
Roles Investigation
Affiliations Research Foundation in Tropical Medicine and the Environment, Buea, Cameroon, Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon
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Dizzle B. Tayong,
Roles Investigation
Affiliations Research Foundation in Tropical Medicine and the Environment, Buea, Cameroon, Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon
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Narcisse V. T. Gandjui,
Roles Investigation
Affiliations Research Foundation in Tropical Medicine and the Environment, Buea, Cameroon, Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon
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Desmond N. Akumtoh,
Roles Investigation
Affiliations Research Foundation in Tropical Medicine and the Environment, Buea, Cameroon, Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon
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Patrick W. N. Chounna,
Roles Investigation
Affiliations Research Foundation in Tropical Medicine and the Environment, Buea, Cameroon, Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon
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Bertrand L. Ndzeshang,
Roles Investigation
Affiliations Research Foundation in Tropical Medicine and the Environment, Buea, Cameroon, Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon
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Sophie Lachaud,
Roles Formal analysis, Investigation, Methodology
Affiliation Janssen Pharmaceutica, Beerse, Belgium
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Fetene Tekle,
Roles Formal analysis, Investigation, Methodology
Affiliation Janssen Pharmaceutica, Beerse, Belgium
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Ludo Quirynen,
Roles Formal analysis, Investigation, Methodology, Project administration, Resources
Affiliation Janssen Pharmaceutica, Beerse, Belgium
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Marc Engelen,
Roles Conceptualization, Data curation, Project administration, Resources, Writing – review & editing
Affiliation Janssen Pharmaceutica, Beerse, Belgium
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Benny Baeten,
Roles Conceptualization, Project administration, Resources, Writing – review & editing
Affiliation Janssen Pharmaceutica, Beerse, Belgium
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Andrew Steven,
Roles Investigation, Resources
Affiliation Department of Parasitology and Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom
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Stephen A. Ward,
Roles Conceptualization, Resources
Affiliation Department of Parasitology and Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom
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Mark J. Taylor,
Roles Conceptualization, Funding acquisition, Resources
Affiliation Department of Parasitology and Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom
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Samuel Wanji,
Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing
Affiliations Research Foundation in Tropical Medicine and the Environment, Buea, Cameroon, Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon
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Joseph D. Turner
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
* E-mail: joseph.turner@lstmed.ac.uk
Affiliation Department of Parasitology and Research Centre for Drugs and Diagnostics, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, United Kingdom
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Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models
- Hanna T. Sjoberg,
- Nicolas Pionnier,
- Ghaith Aljayyoussi,
- Haelly M. Metuge,
- Abdel J. Njouendou,
- Valerine C. Chunda,
- Fanny F. Fombad,
- Dizzle B. Tayong,
- Narcisse V. T. Gandjui,
- Desmond N. Akumtoh
- Published: January 16, 2019
- https://doi.org/10.1371/journal.pntd.0006356