Mansonella perstans microfilaremic individuals are characterized by enhanced type 2 helper T and regulatory T and B cell subsets and dampened systemic innate and adaptive immune responses

• Manuel Ritter ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

  * E-mail: manuel.ritter@ukb.uni-bonn.de

  Affiliation Institute of Medical Microbiology, Immunology and Parasitology, University Hospital of Bonn, Germany

  http://orcid.org/0000-0001-8667-2067

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• Winston Patrick Chounna Ndongmo,

  Roles Formal analysis, Methodology

  Affiliations Parasite and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon, Research Foundation for Tropical Diseases and the Environment (REFOTDE), Buea, Cameroon

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• Abdel Jelil Njouendou,

  Roles Methodology

  Affiliations Parasite and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon, Research Foundation for Tropical Diseases and the Environment (REFOTDE), Buea, Cameroon

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• Nora Nganyewo Nghochuzie,

  Roles Methodology

  Affiliations Parasite and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon, Research Foundation for Tropical Diseases and the Environment (REFOTDE), Buea, Cameroon

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• Lucy Cho Nchang,

  Roles Methodology

  Affiliations Parasite and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon, Research Foundation for Tropical Diseases and the Environment (REFOTDE), Buea, Cameroon

  ⨯
• Dizzle Bita Tayong,

  Roles Project administration

  Affiliations Parasite and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon, Research Foundation for Tropical Diseases and the Environment (REFOTDE), Buea, Cameroon

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• Kathrin Arndts,

  Roles Formal analysis, Writing – review & editing

  Affiliation Institute of Medical Microbiology, Immunology and Parasitology, University Hospital of Bonn, Germany

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• Norman Nausch,

  Roles Writing – review & editing

  Affiliation Department of General Pediatrics, Neonatology, and Pediatric Cardiology, University Children’s Hospital, Medical Faculty, Duesseldorf, Germany

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• Marc Jacobsen,

  Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

  Affiliation Department of General Pediatrics, Neonatology, and Pediatric Cardiology, University Children’s Hospital, Medical Faculty, Duesseldorf, Germany

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• Samuel Wanji ,

  Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work.

  Affiliations Parasite and Vector Research Unit (PAVRU), Department of Microbiology and Parasitology, University of Buea, Buea, Cameroon, Research Foundation for Tropical Diseases and the Environment (REFOTDE), Buea, Cameroon

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• Laura E. Layland ,

  Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work.

  Affiliations Institute of Medical Microbiology, Immunology and Parasitology, University Hospital of Bonn, Germany, German Centre for Infection Research (DZIF), partner site, Bonn-Cologne, Bonn, Germany

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• Achim Hoerauf

  Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work.

  Affiliations Institute of Medical Microbiology, Immunology and Parasitology, University Hospital of Bonn, Germany, German Centre for Infection Research (DZIF), partner site, Bonn-Cologne, Bonn, Germany

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