The glutamine synthetase of Trypanosoma cruzi is required for its resistance to ammonium accumulation and evasion of the parasitophorous vacuole during host-cell infection

• Marcell Crispim,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Laboratory of Biochemistry of Tryps—LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil

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• Flávia Silva Damasceno,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft

  Affiliation Laboratory of Biochemistry of Tryps—LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil

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• Agustín Hernández,

  Roles Investigation, Methodology, Writing – original draft

  Affiliation Laboratory of Biochemistry of Tryps—LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil

  http://orcid.org/0000-0002-7884-8023

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• María Julia Barisón,

  Roles Investigation, Methodology

  Affiliation Laboratory of Biochemistry of Tryps—LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil

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• Ismael Pretto Sauter,

  Roles Methodology

  Affiliation Immunobiology of Leishmania-Macrophage Interaction Laboratory, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil

  http://orcid.org/0000-0002-5824-445X

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• Raphael Souza Pavani,

  Roles Methodology

  Affiliation Special Laboratory of Cell Cycle, Center of Toxins, Immunology and Cell Signalling, Butantan Institute, São Paulo, SP, Brazil

  http://orcid.org/0000-0002-7187-2995

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• Alexandre Santos Moura,

  Roles Methodology

  Affiliation Laboratory of Biochemistry of Tryps—LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil

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• Elizabeth Mieko Furusho Pral,

  Roles Investigation, Methodology

  Affiliation Laboratory of Biochemistry of Tryps—LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil

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• Mauro Cortez,

  Roles Formal analysis, Resources, Supervision

  Affiliation Immunobiology of Leishmania-Macrophage Interaction Laboratory, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil

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• Maria Carolina Elias,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Resources, Supervision

  Affiliation Special Laboratory of Cell Cycle, Center of Toxins, Immunology and Cell Signalling, Butantan Institute, São Paulo, SP, Brazil

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• Ariel Mariano Silber

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: asilber@usp.br

  Affiliation Laboratory of Biochemistry of Tryps—LaBTryps, Department of Parasitology, Institute for Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil

  http://orcid.org/0000-0003-4528-4732

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