Analysis of the efficacy of Taiwanese freeze-dried neurotoxic antivenom against Naja kaouthia, Naja siamensis and Ophiophagus hannah through proteomics and animal model approaches

Chien-Chun Liu; Chen-Hsien You; Po-Jung Wang; Jau-Song Yu; Guo-Jen Huang; Chien-Hsin Liu; Wen-Chin Hsieh; Chih-Chuan Lin

doi:10.1371/journal.pntd.0006138

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Open Access

Peer-reviewed

Research Article

Analysis of the efficacy of Taiwanese freeze-dried neurotoxic antivenom against Naja kaouthia, Naja siamensis and Ophiophagus hannah through proteomics and animal model approaches

Chien-Chun Liu,

Roles Conceptualization, Data curation, Formal analysis, Writing – original draft

Affiliation Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan

http://orcid.org/0000-0002-2324-7976

⨯
Chen-Hsien You,

Roles Data curation, Formal analysis

Affiliation Department of Medicine, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan
⨯
Po-Jung Wang,

Roles Data curation, Formal analysis

Affiliation Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan
⨯
Jau-Song Yu ,

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: yusong@mail.cgu.edu.tw (JSY); bearuncle@yahoo.com (CCL)

Affiliations Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan, Department of Cell and Molecular Biology, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan, Molecular Medicine Research Center, Chang Gung University, Tao-Yuan, Taiwan, Liver Research Center, Chang Gung Memorial Hospital, Linkou, Tao-Yuan, Taiwan
⨯
Guo-Jen Huang,

Roles Formal analysis

Affiliation Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan
⨯
Chien-Hsin Liu,

Roles Resources

Affiliation Center for Research, Diagnostics and Vaccine Development, Centers for Disease Control, Ministry of Health and Welfare, Taipei, Taiwan
⨯
Wen-Chin Hsieh,

Roles Resources

Affiliation Center for Research, Diagnostics and Vaccine Development, Centers for Disease Control, Ministry of Health and Welfare, Taipei, Taiwan
⨯
Chih-Chuan Lin

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: yusong@mail.cgu.edu.tw (JSY); bearuncle@yahoo.com (CCL)

Affiliation Department of Emergency Medicine, Chang Gung Memorial Hospital, Linkou, Tao-Yuan, Taiwan
⨯

Analysis of the efficacy of Taiwanese freeze-dried neurotoxic antivenom against Naja kaouthia, Naja siamensis and Ophiophagus hannah through proteomics and animal model approaches

Chien-Chun Liu,
Chen-Hsien You,
Po-Jung Wang,
Jau-Song Yu,
Guo-Jen Huang,
Chien-Hsin Liu,
Wen-Chin Hsieh,
Chih-Chuan Lin

Published: December 15, 2017
https://doi.org/10.1371/journal.pntd.0006138

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