CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM)

• Anjan Debnath,

  Roles Investigation, Methodology, Resources, Writing – review & editing

  Affiliation Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America

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• Claudia M. Calvet,

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  Affiliations Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America, Cellular Ultrastructure Laboratory, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, RJ, Brazil

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• Gareth Jennings,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America

  http://orcid.org/0000-0001-7986-8491

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• Wenxu Zhou,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Chemistry & Biochemistry, Texas Tech University, Lubbock, Texas, United States of America

  http://orcid.org/0000-0003-0487-1818

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• Alexander Aksenov,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America

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• Madeline R. Luth,

  Roles Investigation

  Affiliation Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America

  http://orcid.org/0000-0001-9059-1200

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• Ruben Abagyan,

  Roles Methodology, Software

  Affiliation Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America

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• W. David Nes,

  Roles Data curation, Methodology, Resources, Supervision

  Affiliation Department of Chemistry & Biochemistry, Texas Tech University, Lubbock, Texas, United States of America

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• James H. McKerrow,

  Roles Funding acquisition, Methodology, Resources, Writing – review & editing

  Affiliation Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America

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• Larissa M. Podust

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: lpodust@ucsd.edu

  Affiliation Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America

  http://orcid.org/0000-0002-8537-8760

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