The Babesia bovis hap2 gene is not required for blood stage replication, but expressed upon in vitro sexual stage induction

• Hala E. Hussein,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliations Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, United States of America, Department of Entomology, Faculty of Science, Cairo University, Giza, Egypt

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• Reginaldo G. Bastos,

  Roles Conceptualization, Software, Writing – review & editing

  Affiliation Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, United States of America

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• David A. Schneider,

  Roles Investigation, Methodology

  Affiliations Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, United States of America, Animal Disease Research Unit, USDA-ARS, Pullman, WA, United States of America

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• Wendell C. Johnson,

  Roles Methodology, Validation

  Affiliation Animal Disease Research Unit, USDA-ARS, Pullman, WA, United States of America

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• Fatma K. Adham,

  Roles Conceptualization, Supervision

  Affiliation Department of Entomology, Faculty of Science, Cairo University, Giza, Egypt

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• William C. Davis,

  Roles Investigation, Methodology

  Affiliation Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, United States of America

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• Jacob M. Laughery,

  Roles Investigation, Methodology

  Affiliation Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, United States of America

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• David R. Herndon,

  Roles Investigation, Methodology, Software

  Affiliation Animal Disease Research Unit, USDA-ARS, Pullman, WA, United States of America

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• Heba F. Alzan,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliations Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, United States of America, Parasitology and Animal Diseases Department, National Research Center, Egypt

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• Massaro W. Ueti ,

  Contributed equally to this work with: Massaro W. Ueti, Carlos E. Suarez

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA, United States of America, Animal Disease Research Unit, USDA-ARS, Pullman, WA, United States of America

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• Carlos E. Suarez

  Contributed equally to this work with: Massaro W. Ueti, Carlos E. Suarez

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: ces@vetmed.wsu.edu

  Affiliation Animal Disease Research Unit, USDA-ARS, Pullman, WA, United States of America

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