Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis

Louise E. Kerry; Elaine E. Pegg; Donald P. Cameron; James Budzak; Gretchen Poortinga; Katherine M. Hannan; Ross D. Hannan; Gloria Rudenko

doi:10.1371/journal.pntd.0005432

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Open Access

Peer-reviewed

Research Article

Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis

Louise E. Kerry,

Affiliation Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, London, United Kingdom
⨯
Elaine E. Pegg,

Affiliation Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, London, United Kingdom
⨯
Donald P. Cameron,

Affiliations ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia, Oncogenic Signalling and Growth Control Program, Peter MacCallum Cancer Centre, Melbourne, Australia
⨯
James Budzak,

Affiliation Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, London, United Kingdom
⨯
Gretchen Poortinga,

Affiliations ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia, Oncogenic Signalling and Growth Control Program, Peter MacCallum Cancer Centre, Melbourne, Australia
⨯
Katherine M. Hannan,

Affiliations ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia, Oncogenic Signalling and Growth Control Program, Peter MacCallum Cancer Centre, Melbourne, Australia
⨯
Ross D. Hannan,

Affiliations ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, Australia, Oncogenic Signalling and Growth Control Program, Peter MacCallum Cancer Centre, Melbourne, Australia
⨯
Gloria Rudenko

* E-mail: gloria.rudenko@imperial.ac.uk

Affiliation Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, London, United Kingdom

http://orcid.org/0000-0003-1884-4933

⨯

Selective inhibition of RNA polymerase I transcription as a potential approach to treat African trypanosomiasis

Louise E. Kerry,
Elaine E. Pegg,
Donald P. Cameron,
James Budzak,
Gretchen Poortinga,
Katherine M. Hannan,
Ross D. Hannan,
Gloria Rudenko

Published: March 6, 2017
https://doi.org/10.1371/journal.pntd.0005432

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