Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo

• Frederick A. Partridge ,

  Contributed equally to this work with: Frederick A. Partridge, Emma A. Murphy, Nicky J. Willis

  Affiliation Centre for Respiratory Biology, UCL Respiratory, Division of Medicine, University College London, London, United Kingdom

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• Emma A. Murphy ,

  Contributed equally to this work with: Frederick A. Partridge, Emma A. Murphy, Nicky J. Willis

  Current address: Liverpool School of Tropical Medicine, Liverpool, United Kingdom

  Affiliation Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

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• Nicky J. Willis ,

  Contributed equally to this work with: Frederick A. Partridge, Emma A. Murphy, Nicky J. Willis

  Affiliation Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom

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• Carole J. R. Bataille,

  Affiliation Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom

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• Ruth Forman,

  Affiliation Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

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• Narinder Heyer-Chauhan,

  Affiliation Centre for Respiratory Biology, UCL Respiratory, Division of Medicine, University College London, London, United Kingdom

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• Bruno Marinič,

  Affiliation Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom

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• Daniel J. C. Sowood,

  Affiliation Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom

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• Graham M. Wynne,

  Affiliation Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom

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• Kathryn J. Else ,

  * E-mail: kathryn.else@manchester.ac.uk (KJE); angela.russell@chem.ox.ac.uk (AJR); d.sattelle@ucl.ac.uk (DBS)

  Affiliation Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom

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• Angela J. Russell ,

  * E-mail: kathryn.else@manchester.ac.uk (KJE); angela.russell@chem.ox.ac.uk (AJR); d.sattelle@ucl.ac.uk (DBS)

  Affiliations Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, United Kingdom, Department of Pharmacology, University of Oxford, Oxford, United Kingdom

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• David B. Sattelle

  * E-mail: kathryn.else@manchester.ac.uk (KJE); angela.russell@chem.ox.ac.uk (AJR); d.sattelle@ucl.ac.uk (DBS)

  Affiliation Centre for Respiratory Biology, UCL Respiratory, Division of Medicine, University College London, London, United Kingdom

  http://orcid.org/0000-0003-0705-5242

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