Development of a PCR Assay to Detect Low Level Trypanosoma cruzi in Blood Specimens Collected with PAXgene Blood DNA Tubes for Clinical Trials Treating Chagas Disease

Open Access

Peer-reviewed

Research Article

Bo Wei ,

* E-mail: bo_wei@merck.com

Affiliation Merck Research Laboratories, Translational Molecular Biomarkers, Rahway, New Jersey, United States of America
⨯
Lei Chen,

Affiliation Merck Research Laboratories, Translational Molecular Biomarkers, Rahway, New Jersey, United States of America
⨯
Miho Kibukawa,

Affiliation Merck Research Laboratories, Translational Molecular Biomarkers, Rahway, New Jersey, United States of America
⨯
John Kang,

Affiliation Merck Research Laboratories, Biometrics Research, Rahway, New Jersey, United States of America
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Hetty Waskin,

Affiliation Merck Research Laboratories, Infectious Disease, Rahway, New Jersey, United States of America
⨯
Matthew Marton

Affiliation Merck Research Laboratories, Companion Diagnostics, Rahway, New Jersey, United States of America
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Trypanosoma cruzi
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Blood
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Polymerase chain reaction
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DNA extraction
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Kinetoplasts
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DNA replication
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DNA isolation
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Chagas disease
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