Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model

Frédéric-Antoine Dauchy; Mélanie Bonhivers; Nicolas Landrein; Denis Dacheux; Pierrette Courtois; Florian Lauruol; Sylvie Daulouède; Philippe Vincendeau; Derrick R. Robinson

doi:10.1371/journal.pntd.0005125

Loading metrics

Open Access

Peer-reviewed

Research Article

Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model

Frédéric-Antoine Dauchy ,

* E-mail: frederic.dauchy@chu-bordeaux.fr

Affiliations University of Bordeaux, laboratoire de parasitologie, France, IRD-CIRAD-University of Bordeaux, France, University Hospital of Bordeaux, Department of infectious and tropical diseases, Hôpital Pellegrin, France
⨯
Mélanie Bonhivers,

Affiliations University of Bordeaux, Microbiologie Fondamentale et Pathogénicité, France, CNRS, Microbiologie Fondamentale et Pathogénicité, France
⨯
Nicolas Landrein,

Affiliations University of Bordeaux, Microbiologie Fondamentale et Pathogénicité, France, CNRS, Microbiologie Fondamentale et Pathogénicité, France
⨯
Denis Dacheux,

Affiliations University of Bordeaux, Microbiologie Fondamentale et Pathogénicité, France, CNRS, Microbiologie Fondamentale et Pathogénicité, France, Bordeaux INP, ENSTBB, Microbiologie Fondamentale et Pathogénicité, France
⨯
Pierrette Courtois,

Affiliations University of Bordeaux, laboratoire de parasitologie, France, IRD-CIRAD-University of Bordeaux, France
⨯
Florian Lauruol,

Affiliations University of Bordeaux, laboratoire de parasitologie, France, IRD-CIRAD-University of Bordeaux, France
⨯
Sylvie Daulouède,

Affiliations University of Bordeaux, laboratoire de parasitologie, France, IRD-CIRAD-University of Bordeaux, France
⨯
Philippe Vincendeau ,

Contributed equally to this work with: Philippe Vincendeau, Derrick R. Robinson

Affiliations University of Bordeaux, laboratoire de parasitologie, France, IRD-CIRAD-University of Bordeaux, France, University Hospital of Bordeaux, laboratoire de parasitologie, Hôpital Pellegrin, France
⨯
Derrick R. Robinson

Contributed equally to this work with: Philippe Vincendeau, Derrick R. Robinson

Affiliations University of Bordeaux, Microbiologie Fondamentale et Pathogénicité, France, CNRS, Microbiologie Fondamentale et Pathogénicité, France
⨯

Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model

Frédéric-Antoine Dauchy,
Mélanie Bonhivers,
Nicolas Landrein,
Denis Dacheux,
Pierrette Courtois,
Florian Lauruol,
Sylvie Daulouède,
Philippe Vincendeau,
Derrick R. Robinson

Published: November 17, 2016
https://doi.org/10.1371/journal.pntd.0005125

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Trypanosoma brucei gambiense
Is the Subject Area "Trypanosoma brucei gambiense" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Trypanosoma
Is the Subject Area "Trypanosoma" applicable to this article?

Thanks for your feedback.
Parasitic diseases
Is the Subject Area "Parasitic diseases" applicable to this article?

Thanks for your feedback.
RNA interference
Is the Subject Area "RNA interference" applicable to this article?

Thanks for your feedback.
Sterols
Is the Subject Area "Sterols" applicable to this article?

Thanks for your feedback.
African trypanosomiasis
Is the Subject Area "African trypanosomiasis" applicable to this article?

Thanks for your feedback.
Trypanosomiasis
Is the Subject Area "Trypanosomiasis" applicable to this article?

Thanks for your feedback.