Precisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype-Specific Neutralizing Antibody Responses

• Stefan W. Metz ,

  Contributed equally to this work with: Stefan W. Metz, Shaomin Tian

  Affiliation Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, United States of America

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• Shaomin Tian ,

  Contributed equally to this work with: Stefan W. Metz, Shaomin Tian

  Affiliation Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, United States of America

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• Gabriel Hoekstra,

  Affiliation Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, United States of America

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• Xianwen Yi,

  Affiliation Lineberger Comprehensive Center, University of North Carolina, Chapel Hill, North Carolina, United States of America

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• Michelle Stone,

  Affiliation Liquidia Technologies, Research Triangle Park, North Carolina, United States of America

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• Katie Horvath,

  Affiliation Liquidia Technologies, Research Triangle Park, North Carolina, United States of America

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• Michael J. Miley,

  Affiliation Department of Pharmacology, University of North Carolina, Chapel Hill, North Carolina, United States of America

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• Joseph DeSimone,

  Affiliations Lineberger Comprehensive Center, University of North Carolina, Chapel Hill, North Carolina, United States of America, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, United States of America, Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina, United States of America, Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, United States of America, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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• Chris J. Luft ,

  * E-mail: jluft@email.unc.edu (CJL); deSilva@med.unc.edu (AMdS)

  Affiliations Lineberger Comprehensive Center, University of North Carolina, Chapel Hill, North Carolina, United States of America, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina, United States of America

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• Aravinda M. de Silva

  * E-mail: jluft@email.unc.edu (CJL); deSilva@med.unc.edu (AMdS)

  Affiliation Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, United States of America

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