Compounds Derived from the Bhutanese Daisy, Ajania nubigena, Demonstrate Dual Anthelmintic Activity against Schistosoma mansoni and Trichuris muris

Phurpa Wangchuk; Mark S. Pearson; Paul R. Giacomin; Luke Becker; Javier Sotillo; Darren Pickering; Michael J. Smout; Alex Loukas

doi:10.1371/journal.pntd.0004908

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Open Access

Peer-reviewed

Research Article

Compounds Derived from the Bhutanese Daisy, Ajania nubigena, Demonstrate Dual Anthelmintic Activity against Schistosoma mansoni and Trichuris muris

Phurpa Wangchuk ,

* E-mail: phurpa.wangchuk@jcu.edu.au

Affiliation Centre for Biodiscovery and Molecular Development of Therapeutics, Queensland Tropical Health Alliance, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns Campus, Cairns, Australia

http://orcid.org/0000-0002-4381-7382

⨯
Mark S. Pearson,

Affiliation Centre for Biodiscovery and Molecular Development of Therapeutics, Queensland Tropical Health Alliance, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns Campus, Cairns, Australia
⨯
Paul R. Giacomin,

Affiliation Centre for Biodiscovery and Molecular Development of Therapeutics, Queensland Tropical Health Alliance, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns Campus, Cairns, Australia
⨯
Luke Becker,

Affiliation Centre for Biodiscovery and Molecular Development of Therapeutics, Queensland Tropical Health Alliance, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns Campus, Cairns, Australia
⨯
Javier Sotillo,

Affiliation Centre for Biodiscovery and Molecular Development of Therapeutics, Queensland Tropical Health Alliance, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns Campus, Cairns, Australia
⨯
Darren Pickering,

Affiliation Centre for Biodiscovery and Molecular Development of Therapeutics, Queensland Tropical Health Alliance, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns Campus, Cairns, Australia
⨯
Michael J. Smout ,

Contributed equally to this work with: Michael J. Smout, Alex Loukas

Affiliation Centre for Biodiscovery and Molecular Development of Therapeutics, Queensland Tropical Health Alliance, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns Campus, Cairns, Australia
⨯
Alex Loukas

Contributed equally to this work with: Michael J. Smout, Alex Loukas

Affiliation Centre for Biodiscovery and Molecular Development of Therapeutics, Queensland Tropical Health Alliance, Australian Institute of Tropical Health and Medicine, James Cook University, Cairns Campus, Cairns, Australia
⨯

Compounds Derived from the Bhutanese Daisy, Ajania nubigena, Demonstrate Dual Anthelmintic Activity against Schistosoma mansoni and Trichuris muris

Phurpa Wangchuk,
Mark S. Pearson,
Paul R. Giacomin,
Luke Becker,
Javier Sotillo,
Darren Pickering,
Michael J. Smout,
Alex Loukas

Published: August 4, 2016
https://doi.org/10.1371/journal.pntd.0004908

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