Immunohistochemical Analysis of Scarring Trachoma Indicates Infiltration by Natural Killer and Undefined CD45 Negative Cells

Victor H. Hu; Philip J. Luthert; Tamsyn Derrick; James Pullin; Helen A. Weiss; Patrick Massae; Tara Mtuy; William Makupa; David Essex; David C. W. Mabey; Robin L. Bailey; Martin J. Holland; Matthew J. Burton

doi:10.1371/journal.pntd.0004734

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Open Access

Peer-reviewed

Research Article

Immunohistochemical Analysis of Scarring Trachoma Indicates Infiltration by Natural Killer and Undefined CD45 Negative Cells

Victor H. Hu,

Affiliations International Centre for Eye Health, Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom, Kilimanjaro Christian Medical Centre, Moshi, Tanzania
⨯
Philip J. Luthert,

Affiliation UCL Institute of Ophthalmology, London, United Kingdom
⨯
Tamsyn Derrick ,

* E-mail: tamsyn.derrick@lshtm.ac.uk

Affiliations Kilimanjaro Christian Medical Centre, Moshi, Tanzania, Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

http://orcid.org/0000-0002-1458-6503

⨯
James Pullin,

Affiliation UCL Institute of Ophthalmology, London, United Kingdom
⨯
Helen A. Weiss,

Affiliation Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
⨯
Patrick Massae,

Affiliation Kilimanjaro Christian Medical Centre, Moshi, Tanzania
⨯
Tara Mtuy,

Affiliations International Centre for Eye Health, Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom, Kilimanjaro Christian Medical Centre, Moshi, Tanzania
⨯
William Makupa,

Affiliation Kilimanjaro Christian Medical Centre, Moshi, Tanzania
⨯
David Essex,

Affiliation UCL Institute of Ophthalmology, London, United Kingdom
⨯
David C. W. Mabey,

Affiliation Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
⨯
Robin L. Bailey,

Affiliation Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
⨯
Martin J. Holland,

Affiliation Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
⨯
Matthew J. Burton

Affiliations International Centre for Eye Health, Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom, Kilimanjaro Christian Medical Centre, Moshi, Tanzania
⨯

Immunohistochemical Analysis of Scarring Trachoma Indicates Infiltration by Natural Killer and Undefined CD45 Negative Cells

Victor H. Hu,
Philip J. Luthert,
Tamsyn Derrick,
James Pullin,
Helen A. Weiss,
Patrick Massae,
Tara Mtuy,
William Makupa,
David Essex,
David C. W. Mabey

Published: May 24, 2016
https://doi.org/10.1371/journal.pntd.0004734

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Inflammation
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NK cells
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Cytotoxic T cells
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Cell staining
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Trachoma
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T cells
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Immunohistochemistry techniques
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Chlamydia trachomatis
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