Trypanosoma brucei DHFR-TS Revisited: Characterisation of a Bifunctional and Highly Unstable Recombinant Dihydrofolate Reductase-Thymidylate Synthase

• Marc W. Gibson,

  Current address: Velocity, University of Waterloo, Waterloo, Ontario, Canada

  Affiliation Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, United Kingdom

  ⨯
• Simon Dewar,

  Affiliation Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, United Kingdom

  ⨯
• Han B. Ong,

  Current address: Cell Surface Signalling Laboratory, Wellcome Trust Sanger Institute, Cambridge, United Kingdom

  Affiliation Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, United Kingdom

  ⨯
• Natasha Sienkiewicz,

  Affiliation Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, United Kingdom

  ⨯
• Alan H. Fairlamb

  * E-mail: a.h.fairlamb@dundee.ac.uk

  Affiliation Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee, United Kingdom

  http://orcid.org/0000-0001-5134-0329

  ⨯