The Viral Polymerase Inhibitor 7-Deaza-2’-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model

• Joanna Zmurko,

  Affiliation Laboratory of Virology and Chemotherapy, KU Leuven - University of Leuven, Leuven, Belgium

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• Rafael E. Marques,

  Affiliation Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

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• Dominique Schols,

  Affiliation Laboratory of Virology and Chemotherapy, KU Leuven - University of Leuven, Leuven, Belgium

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• Erik Verbeken,

  Affiliation Department of Pathology, University of Leuven and Leuven University Hospitals, Leuven, Belgium

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• Suzanne J.F. Kaptein ,

  ¶‡ These joint senior authors contributed equally to this work.

  Affiliation Laboratory of Virology and Chemotherapy, KU Leuven - University of Leuven, Leuven, Belgium

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• Johan Neyts

  * E-mail: Johan.Neyts@rega.kuleuven.be

  ¶‡ These joint senior authors contributed equally to this work.

  Affiliation Laboratory of Virology and Chemotherapy, KU Leuven - University of Leuven, Leuven, Belgium

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