Identification of Trypanocidal Activity for Known Clinical Compounds Using a New Trypanosoma cruzi Hit-Discovery Screening Cascade

• Manu De Rycker ,

  * E-mail: m.derycker@dundee.ac.uk (MDR); d.w.gray@dundee.ac.uk (DWG)

  Affiliation Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee, United Kingdom

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• John Thomas,

  Affiliation Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee, United Kingdom

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• Jennifer Riley,

  Affiliation Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee, United Kingdom

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• Stephen J. Brough,

  Affiliation GlaxoSmithKline, Biological Sciences, Medicines Research Centre, Stevenage, Hertfordshire, United Kingdom

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• Tim J. Miles,

  Affiliation GlaxoSmithKline, Diseases of the Developing World, Parque Tecnologico de Madrid, Servero Ochoa, Madrid, Spain

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• David W. Gray

  * E-mail: m.derycker@dundee.ac.uk (MDR); d.w.gray@dundee.ac.uk (DWG)

  Affiliation Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee, United Kingdom

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