Intradermal Immunization of Leishmania donovani Centrin Knock-Out Parasites in Combination with Salivary Protein LJM19 from Sand Fly Vector Induces a Durable Protective Immune Response in Hamsters

• Jacqueline Araújo Fiuza,

  Affiliations Laboratory of Emerging Pathogens, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, United States of America, Laboratório de Imunologia Celular e Molecular, Centro de Pesquisas René Rachou—Fiocruz Minas, Belo Horizonte, Minas Gerais, Brasil

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• Ranadhir Dey,

  Affiliation Laboratory of Emerging Pathogens, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Dwann Davenport,

  Affiliation Laboratory of Emerging Pathogens, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Maha Abdeladhim,

  Affiliation Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America

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• Claudio Meneses,

  Affiliation Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America

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• Fabiano Oliveira,

  Affiliation Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America

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• Shaden Kamhawi,

  Affiliation Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America

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• Jesus G. Valenzuela,

  Affiliation Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America

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• Sreenivas Gannavaram ,

  * E-mail: sreenivas.gannavaram@fda.hhs.gov (SG); hira.nakhasi@fda.hhs.gov (HLN)

  Affiliation Laboratory of Emerging Pathogens, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, United States of America

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• Hira L. Nakhasi

  * E-mail: sreenivas.gannavaram@fda.hhs.gov (SG); hira.nakhasi@fda.hhs.gov (HLN)

  Affiliation Laboratory of Emerging Pathogens, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, United States of America

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