The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development

Peter D. Ziniel; Bhargava Karumudi; Andrew H. Barnard; Ethan M. S. Fisher; Gregory R. J. Thatcher; Larissa M. Podust; David L. Williams

doi:10.1371/journal.pntd.0004279

Loading metrics

Open Access

Peer-reviewed

Research Article

The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development

Peter D. Ziniel,

Current address: Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America

Affiliation Department of Immunology & Microbiology, Rush University Medical Center, Chicago, Illinois, United States of America
⨯
Bhargava Karumudi,

Affiliation Department of Medicinal Chemistry and Pharmacognosy, University of Illinois College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Andrew H. Barnard,

Affiliation Department of Immunology & Microbiology, Rush University Medical Center, Chicago, Illinois, United States of America
⨯
Ethan M. S. Fisher,

Current address: Illinois Mathematics and Science Academy, Aurora, Illinois, United States of America

Affiliation Department of Immunology & Microbiology, Rush University Medical Center, Chicago, Illinois, United States of America
⨯
Gregory R. J. Thatcher,

Affiliation Department of Medicinal Chemistry and Pharmacognosy, University of Illinois College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Larissa M. Podust,

Affiliation Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, United States of America
⨯
David L. Williams

* E-mail: David_L_Williams@rush.edu

Affiliation Department of Immunology & Microbiology, Rush University Medical Center, Chicago, Illinois, United States of America
⨯

The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development

Peter D. Ziniel,
Bhargava Karumudi,
Andrew H. Barnard,
Ethan M. S. Fisher,
Gregory R. J. Thatcher,
Larissa M. Podust,
David L. Williams

Published: December 29, 2015
https://doi.org/10.1371/journal.pntd.0004279

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Eggs
Is the Subject Area "Eggs" applicable to this article?

Thanks for your feedback.
Schistosoma mansoni
Is the Subject Area "Schistosoma mansoni" applicable to this article?

Thanks for your feedback.
Schistosoma
Is the Subject Area "Schistosoma" applicable to this article?

Thanks for your feedback.
Larvae
Is the Subject Area "Larvae" applicable to this article?

Thanks for your feedback.
Polymerase chain reaction
Is the Subject Area "Polymerase chain reaction" applicable to this article?

Thanks for your feedback.
Protein metabolism
Is the Subject Area "Protein metabolism" applicable to this article?

Thanks for your feedback.
Schistosomiasis
Is the Subject Area "Schistosomiasis" applicable to this article?

Thanks for your feedback.
Messenger RNA
Is the Subject Area "Messenger RNA" applicable to this article?

Thanks for your feedback.