Assessment of Inhibitors of Pathogenic Crimean-Congo Hemorrhagic Fever Virus Strains Using Virus-Like Particles

Marko Zivcec; Maureen G. Metcalfe; César G. Albariño; Lisa W. Guerrero; Scott D. Pegan; Christina F. Spiropoulou; Éric Bergeron

doi:10.1371/journal.pntd.0004259

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Peer-reviewed

Research Article

Assessment of Inhibitors of Pathogenic Crimean-Congo Hemorrhagic Fever Virus Strains Using Virus-Like Particles

Marko Zivcec,

Affiliation Viral Special Pathogens Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Maureen G. Metcalfe,

Affiliation Infectious Disease Pathology Branch, Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
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César G. Albariño,

Affiliation Viral Special Pathogens Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯
Lisa W. Guerrero,

Affiliation Viral Special Pathogens Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
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Scott D. Pegan,

Affiliation Department of Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, Georgia, United States of America
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Christina F. Spiropoulou,

Affiliation Viral Special Pathogens Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
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Éric Bergeron

* E-mail: ebergeron@cdc.gov

Affiliation Viral Special Pathogens Branch, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
⨯

Assessment of Inhibitors of Pathogenic Crimean-Congo Hemorrhagic Fever Virus Strains Using Virus-Like Particles

Marko Zivcec,
Maureen G. Metcalfe,
César G. Albariño,
Lisa W. Guerrero,
Scott D. Pegan,
Christina F. Spiropoulou,
Éric Bergeron

Published: December 1, 2015
https://doi.org/10.1371/journal.pntd.0004259

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Transfection
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Glycoproteins
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Cell signaling
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Crimean-Congo hemorrhagic fever
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Plasmid construction
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Signal inhibition
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Viral entry
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