BoHV-4-Based Vector Single Heterologous Antigen Delivery Protects STAT1(-/-) Mice from Monkeypoxvirus Lethal Challenge

Valentina Franceschi; Scott Parker; Sarah Jacca; Ryan W. Crump; Konstantin Doronin; Edguardo Hembrador; Daniela Pompilio; Giulia Tebaldi; Ryan D. Estep; Scott W. Wong; Mark R. Buller; Gaetano Donofrio

doi:10.1371/journal.pntd.0003850

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Open Access

Peer-reviewed

Research Article

BoHV-4-Based Vector Single Heterologous Antigen Delivery Protects STAT1^(-/-) Mice from Monkeypoxvirus Lethal Challenge

Valentina Franceschi ,

Contributed equally to this work with: Valentina Franceschi, Scott Parker, Sarah Jacca

Affiliation Department of Medical-Veterinary Science, University of Parma, Parma, Italy
⨯
Scott Parker ,

Contributed equally to this work with: Valentina Franceschi, Scott Parker, Sarah Jacca

Affiliation Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America
⨯
Sarah Jacca ,

Contributed equally to this work with: Valentina Franceschi, Scott Parker, Sarah Jacca

Affiliation Department of Medical-Veterinary Science, University of Parma, Parma, Italy
⨯
Ryan W. Crump,

Affiliation Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America
⨯
Konstantin Doronin,

Affiliation Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America
⨯
Edguardo Hembrador,

Affiliation Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America
⨯
Daniela Pompilio,

Affiliation Department of Medical-Veterinary Science, University of Parma, Parma, Italy
⨯
Giulia Tebaldi,

Affiliation Department of Medical-Veterinary Science, University of Parma, Parma, Italy
⨯
Ryan D. Estep,

Affiliation Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, United States of America
⨯
Scott W. Wong,

Affiliation Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, United States of America
⨯
Mark R. Buller,

Affiliation Molecular Microbiology and Immunology, Saint Louis University School of Medicine, St. Louis, Missouri, United States of America
⨯
Gaetano Donofrio

* E-mail: gaetano.donofrio@unipr.it

Affiliation Department of Medical-Veterinary Science, University of Parma, Parma, Italy
⨯

BoHV-4-Based Vector Single Heterologous Antigen Delivery Protects STAT1^(-/-) Mice from Monkeypoxvirus Lethal Challenge

Valentina Franceschi,
Scott Parker,
Sarah Jacca,
Ryan W. Crump,
Konstantin Doronin,
Edguardo Hembrador,
Daniela Pompilio,
Giulia Tebaldi,
Ryan D. Estep,
Scott W. Wong

Published: June 18, 2015
https://doi.org/10.1371/journal.pntd.0003850

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