Signatures of Adaptation in Human Invasive Salmonella Typhimurium ST313 Populations from Sub-Saharan Africa

Chinyere K. Okoro; Lars Barquist; Thomas R. Connor; Simon R. Harris; Simon Clare; Mark P. Stevens; Mark J. Arends; Christine Hale; Leanne Kane; Derek J. Pickard; Jennifer Hill; Katherine Harcourt; Julian Parkhill; Gordon Dougan; Robert A. Kingsley

doi:10.1371/journal.pntd.0003611

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Open Access

Peer-reviewed

Research Article

Signatures of Adaptation in Human Invasive Salmonella Typhimurium ST313 Populations from Sub-Saharan Africa

Chinyere K. Okoro ,

* E-mail: cko21@medschl.cam.ac.uk

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Lars Barquist,

Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom, Institute for Molecular Infection Biology, University of Wurzburg, Wuerzburg, Germany
⨯
Thomas R. Connor,

Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom, Cardiff School of Biosciences, Cardiff University, Cardiff, United Kingdom
⨯
Simon R. Harris,

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Simon Clare,

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Mark P. Stevens,

Affiliation The Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Scotland, United Kingdom
⨯
Mark J. Arends,

Affiliations Department of Pathology, University of Cambridge, Addenbrokes Hospital, Cambridge, United Kingdom, Edinburgh Cancer Research Centre, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom
⨯
Christine Hale,

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Leanne Kane,

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Derek J. Pickard,

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Jennifer Hill,

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Katherine Harcourt,

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Julian Parkhill,

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Gordon Dougan,

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Robert A. Kingsley

Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom, Institute of Food Research, Norwich Research Park, Norwich, Norfolk, United Kingdom
⨯

Signatures of Adaptation in Human Invasive Salmonella Typhimurium ST313 Populations from Sub-Saharan Africa

Chinyere K. Okoro,
Lars Barquist,
Thomas R. Connor,
Simon R. Harris,
Simon Clare,
Mark P. Stevens,
Mark J. Arends,
Christine Hale,
Leanne Kane,
Derek J. Pickard

Published: March 24, 2015
https://doi.org/10.1371/journal.pntd.0003611

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