A Randomised, Double-Blind, Controlled Efficacy Trial of the LiESP/QA-21 Vaccine in Naïve Dogs Exposed to Two Leishmania infantum Transmission Seasons

Gaetano Oliva; Javier Nieto; Valentina Foglia Manzillo; Silvia Cappiello; Eleonora Fiorentino; Trentina Di Muccio; Aldo Scalone; Javier Moreno; Carmen Chicharro; Eugenia Carrillo; Therese Butaud; Laurie Guegand; Virginie Martin; Anne-Marie Cuisinier; David McGahie; Sylvie Gueguen; Carmen Cañavate; Luigi Gradoni

doi:10.1371/journal.pntd.0003213

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Peer-reviewed

Research Article

A Randomised, Double-Blind, Controlled Efficacy Trial of the LiESP/QA-21 Vaccine in Naïve Dogs Exposed to Two Leishmania infantum Transmission Seasons

Gaetano Oliva,

Affiliation Department of Veterinary Clinical Sciences, University Federico II, Naples, Italy
⨯
Javier Nieto,

Affiliation Leishmaniasis and Chagas Disease Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Spain
⨯
Valentina Foglia Manzillo,

Affiliation Department of Veterinary Clinical Sciences, University Federico II, Naples, Italy
⨯
Silvia Cappiello,

Affiliation Department of Veterinary Clinical Sciences, University Federico II, Naples, Italy
⨯
Eleonora Fiorentino,

Affiliation Unit of Vector-borne Diseases and International Health, MIPI Department, Istituto Superiore di Sanità, Rome, Italy
⨯
Trentina Di Muccio,

Affiliation Unit of Vector-borne Diseases and International Health, MIPI Department, Istituto Superiore di Sanità, Rome, Italy
⨯
Aldo Scalone,

Affiliation Unit of Vector-borne Diseases and International Health, MIPI Department, Istituto Superiore di Sanità, Rome, Italy
⨯
Javier Moreno,

Affiliation Leishmaniasis and Chagas Disease Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Spain
⨯
Carmen Chicharro,

Affiliation Leishmaniasis and Chagas Disease Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Spain
⨯
Eugenia Carrillo,

Affiliation Leishmaniasis and Chagas Disease Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Spain
⨯
Therese Butaud,

Affiliation Safety and Efficacy Unit, Biological R&D, VIRBAC BIO3, Carros, France
⨯
Laurie Guegand,

Affiliation Safety and Efficacy Unit, Biological R&D, VIRBAC BIO3, Carros, France
⨯
Virginie Martin,

Affiliation Safety and Efficacy Unit, Biological R&D, VIRBAC BIO3, Carros, France
⨯
Anne-Marie Cuisinier,

Affiliation Safety and Efficacy Unit, Biological R&D, VIRBAC BIO3, Carros, France
⨯
David McGahie ,

* E-mail: david.mcgahie@virbac.com

Affiliation Medical Department, VIRBAC, Carros, France
⨯
Sylvie Gueguen,

Affiliation Safety and Efficacy Unit, Biological R&D, VIRBAC BIO3, Carros, France
⨯
Carmen Cañavate,

Affiliation Leishmaniasis and Chagas Disease Unit, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Spain
⨯
[ ... ],
Luigi Gradoni

Affiliation Unit of Vector-borne Diseases and International Health, MIPI Department, Istituto Superiore di Sanità, Rome, Italy
⨯
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A Randomised, Double-Blind, Controlled Efficacy Trial of the LiESP/QA-21 Vaccine in Naïve Dogs Exposed to Two Leishmania infantum Transmission Seasons

Gaetano Oliva,
Javier Nieto,
Valentina Foglia Manzillo,
Silvia Cappiello,
Eleonora Fiorentino,
Trentina Di Muccio,
Aldo Scalone,
Javier Moreno,
Carmen Chicharro,
Eugenia Carrillo

Published: October 9, 2014
https://doi.org/10.1371/journal.pntd.0003213

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