High Content Image-Based Screening of a Protease Inhibitor Library Reveals Compounds Broadly Active against Rift Valley Fever Virus and Other Highly Pathogenic RNA Viruses

Open Access

Peer-reviewed

Research Article

Rajini Mudhasani,

Affiliation Molecular and Translational Sciences Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America
⨯
Krishna P. Kota,

Affiliation Molecular and Translational Sciences Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America
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Cary Retterer,

Affiliation Molecular and Translational Sciences Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America
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Julie P. Tran,

Affiliation Molecular and Translational Sciences Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America
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Chris A. Whitehouse,

Affiliation Molecular and Translational Sciences Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America
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Sina Bavari

* E-mail: sina.bavari.civ@mail.mil

Affiliation Molecular and Translational Sciences Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America
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Rift Valley fever virus
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HeLa cells
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Golgi apparatus
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Library screening
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Ebola virus
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RNA viruses
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Image analysis
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Viral pathogens
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