MicroRNA-30e* Suppresses Dengue Virus Replication by Promoting NF-κB–Dependent IFN Production

Xun Zhu; Zhenjian He; Yiwen Hu; Weitao Wen; Cuiji Lin; Jianchen Yu; Jing Pan; Ran Li; Haijing Deng; Shaowei Liao; Jie Yuan; Jueheng Wu; Jun Li; Mengfeng Li

doi:10.1371/journal.pntd.0003088

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Peer-reviewed

Research Article

MicroRNA-30e* Suppresses Dengue Virus Replication by Promoting NF-κB–Dependent IFN Production

Xun Zhu ,

Contributed equally to this work with: Xun Zhu, Zhenjian He, Yiwen Hu

Affiliations Key Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, China, Guangdong Province Key Laboratory of Functional Molecules in Oceanic Microorganism (Sun Yat-sen University), Bureau of Education, Guangzhou, China, Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Zhenjian He ,

Contributed equally to this work with: Xun Zhu, Zhenjian He, Yiwen Hu

Affiliations Key Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, China, Guangdong Province Key Laboratory of Functional Molecules in Oceanic Microorganism (Sun Yat-sen University), Bureau of Education, Guangzhou, China, Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Yiwen Hu ,

Contributed equally to this work with: Xun Zhu, Zhenjian He, Yiwen Hu

Affiliations Key Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, China, Guangdong Province Key Laboratory of Functional Molecules in Oceanic Microorganism (Sun Yat-sen University), Bureau of Education, Guangzhou, China, Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Weitao Wen,

Affiliations Key Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, China, Guangdong Province Key Laboratory of Functional Molecules in Oceanic Microorganism (Sun Yat-sen University), Bureau of Education, Guangzhou, China, Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Cuiji Lin,

Affiliations Key Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, China, Guangdong Province Key Laboratory of Functional Molecules in Oceanic Microorganism (Sun Yat-sen University), Bureau of Education, Guangzhou, China, Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Jianchen Yu,

Affiliations Key Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, China, Guangdong Province Key Laboratory of Functional Molecules in Oceanic Microorganism (Sun Yat-sen University), Bureau of Education, Guangzhou, China, Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Jing Pan,

Affiliation Department of Clinical Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Ran Li,

Affiliation Department of Clinical Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Haijing Deng,

Affiliation Department of Clinical Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Shaowei Liao,

Affiliation Department of Clinical Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Jie Yuan,

Affiliations Key Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, China, Guangdong Province Key Laboratory of Functional Molecules in Oceanic Microorganism (Sun Yat-sen University), Bureau of Education, Guangzhou, China, Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Jueheng Wu,

Affiliations Key Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, China, Guangdong Province Key Laboratory of Functional Molecules in Oceanic Microorganism (Sun Yat-sen University), Bureau of Education, Guangzhou, China, Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Jun Li,

Affiliations Key Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, China, Guangdong Province Key Laboratory of Functional Molecules in Oceanic Microorganism (Sun Yat-sen University), Bureau of Education, Guangzhou, China, Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯
Mengfeng Li

* E-mail: limf@mail.sysu.edu.cn

Affiliations Key Laboratory of Tropical Disease Control (Sun Yat-sen University), Ministry of Education, Guangzhou, China, Guangdong Province Key Laboratory of Functional Molecules in Oceanic Microorganism (Sun Yat-sen University), Bureau of Education, Guangzhou, China, Department of Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
⨯

MicroRNA-30e* Suppresses Dengue Virus Replication by Promoting NF-κB–Dependent IFN Production

Xun Zhu,
Zhenjian He,
Yiwen Hu,
Weitao Wen,
Cuiji Lin,
Jianchen Yu,
Jing Pan,
Ran Li,
Haijing Deng,
Shaowei Liao

Published: August 14, 2014
https://doi.org/10.1371/journal.pntd.0003088

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