Evaluation of Antiviral Efficacy of Ribavirin, Arbidol, and T-705 (Favipiravir) in a Mouse Model for Crimean-Congo Hemorrhagic Fever

Lisa Oestereich; Toni Rieger; Melanie Neumann; Christian Bernreuther; Maria Lehmann; Susanne Krasemann; Stephanie Wurr; Petra Emmerich; Xavier de Lamballerie; Stephan Ölschläger; Stephan Günther

doi:10.1371/journal.pntd.0002804

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Open Access

Peer-reviewed

Research Article

Evaluation of Antiviral Efficacy of Ribavirin, Arbidol, and T-705 (Favipiravir) in a Mouse Model for Crimean-Congo Hemorrhagic Fever

Lisa Oestereich ,

Contributed equally to this work with: Lisa Oestereich, Toni Rieger

Affiliations Department of Virology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany, German Centre for Infection Research (DZIF), Hamburg, Germany
⨯
Toni Rieger ,

Contributed equally to this work with: Lisa Oestereich, Toni Rieger

Affiliations Department of Virology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany, German Centre for Infection Research (DZIF), Hamburg, Germany
⨯
Melanie Neumann,

Affiliation Mouse Pathology Core Facility, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
⨯
Christian Bernreuther,

Affiliation Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
⨯
Maria Lehmann,

Affiliations Department of Virology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany, German Centre for Infection Research (DZIF), Hamburg, Germany
⨯
Susanne Krasemann,

Affiliation Mouse Pathology Core Facility, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
⨯
Stephanie Wurr,

Affiliations Department of Virology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany, German Centre for Infection Research (DZIF), Hamburg, Germany
⨯
Petra Emmerich,

Affiliations Department of Virology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany, German Centre for Infection Research (DZIF), Hamburg, Germany
⨯
Xavier de Lamballerie,

Affiliation Aix Marseille Université, IRD French Institute of Research for Development, EHESP French School of Public Health, UMR_D 190 “Emergence des Pathologies Virales”, Marseille, France
⨯
Stephan Ölschläger ,

Current address: altona Diagnostics GmbH, Hamburg, Germany

¶SÖ and SG also contributed equally to this work.

Affiliation Department of Virology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany
⨯
Stephan Günther

* E-mail: guenther@bni.uni-hamburg.de

¶SÖ and SG also contributed equally to this work.

Affiliations Department of Virology, Bernhard-Nocht-Institute for Tropical Medicine, Hamburg, Germany, German Centre for Infection Research (DZIF), Hamburg, Germany
⨯

Evaluation of Antiviral Efficacy of Ribavirin, Arbidol, and T-705 (Favipiravir) in a Mouse Model for Crimean-Congo Hemorrhagic Fever

Lisa Oestereich,
Toni Rieger,
Melanie Neumann,
Christian Bernreuther,
Maria Lehmann,
Susanne Krasemann,
Stephanie Wurr,
Petra Emmerich,
Xavier de Lamballerie,
Stephan Ölschläger

Published: May 1, 2014
https://doi.org/10.1371/journal.pntd.0002804

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