Enhanced Protective Efficacy of Nonpathogenic Recombinant Leishmania tarentolae Expressing Cysteine Proteinases Combined with a Sand Fly Salivary Antigen

Farnaz Zahedifard; Elham Gholami; Tahereh Taheri; Yasaman Taslimi; Fatemeh Doustdari; Negar Seyed; Fatemeh Torkashvand; Claudio Meneses; Barbara Papadopoulou; Shaden Kamhawi; Jesus G. Valenzuela; Sima Rafati

doi:10.1371/journal.pntd.0002751

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Open Access

Peer-reviewed

Research Article

Enhanced Protective Efficacy of Nonpathogenic Recombinant Leishmania tarentolae Expressing Cysteine Proteinases Combined with a Sand Fly Salivary Antigen

Farnaz Zahedifard ,

Contributed equally to this work with: Farnaz Zahedifard, Elham Gholami

Affiliation Molecular Immunology and Vaccine Research Laboratory, Pasteur Institute of Iran, Tehran, Iran
⨯
Elham Gholami ,

Contributed equally to this work with: Farnaz Zahedifard, Elham Gholami

Affiliation Molecular Immunology and Vaccine Research Laboratory, Pasteur Institute of Iran, Tehran, Iran
⨯
Tahereh Taheri,

Affiliation Molecular Immunology and Vaccine Research Laboratory, Pasteur Institute of Iran, Tehran, Iran
⨯
Yasaman Taslimi,

Affiliation Molecular Immunology and Vaccine Research Laboratory, Pasteur Institute of Iran, Tehran, Iran
⨯
Fatemeh Doustdari,

Affiliation Molecular Immunology and Vaccine Research Laboratory, Pasteur Institute of Iran, Tehran, Iran
⨯
Negar Seyed,

Affiliation Molecular Immunology and Vaccine Research Laboratory, Pasteur Institute of Iran, Tehran, Iran
⨯
Fatemeh Torkashvand,

Affiliation Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
⨯
Claudio Meneses,

Affiliation Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institute of Health, Rockville, Maryland, United States of America
⨯
Barbara Papadopoulou,

Affiliation Research Centre in Infectious Disease, CHUL Research Centre (CHU de Québec Research Centre) and Department of Microbiology, Infectious Disease and Immunology, Laval University, Quebec, Canada
⨯
Shaden Kamhawi,

Affiliation Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institute of Health, Rockville, Maryland, United States of America
⨯
Jesus G. Valenzuela,

Affiliation Vector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institute of Health, Rockville, Maryland, United States of America
⨯
Sima Rafati

* E-mail: s_rafati@yahoo.com, sima-rafatisy@pasteur.ac.ir

Affiliation Molecular Immunology and Vaccine Research Laboratory, Pasteur Institute of Iran, Tehran, Iran
⨯

Enhanced Protective Efficacy of Nonpathogenic Recombinant Leishmania tarentolae Expressing Cysteine Proteinases Combined with a Sand Fly Salivary Antigen

Farnaz Zahedifard,
Elham Gholami,
Tahereh Taheri,
Yasaman Taslimi,
Fatemeh Doustdari,
Negar Seyed,
Fatemeh Torkashvand,
Claudio Meneses,
Barbara Papadopoulou,
Shaden Kamhawi

Published: March 27, 2014
https://doi.org/10.1371/journal.pntd.0002751

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