Gene Amplification and Point Mutations in Pyrimidine Metabolic Genes in 5-Fluorouracil Resistant Leishmania infantum

Open Access

Peer-reviewed

Research Article

Jean-François Ritt,

Affiliation Centre de recherche en Infectiologie du CHU de Québec and Département de Microbiologie, Infectiologie et Immunologie, Université Laval, Québec City, Québec, Canada
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Frédéric Raymond,

Affiliation Centre de recherche en Infectiologie du CHU de Québec and Département de Microbiologie, Infectiologie et Immunologie, Université Laval, Québec City, Québec, Canada
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Philippe Leprohon,

Affiliation Centre de recherche en Infectiologie du CHU de Québec and Département de Microbiologie, Infectiologie et Immunologie, Université Laval, Québec City, Québec, Canada
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Danielle Légaré,

Affiliation Centre de recherche en Infectiologie du CHU de Québec and Département de Microbiologie, Infectiologie et Immunologie, Université Laval, Québec City, Québec, Canada
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Jacques Corbeil,

Affiliation Centre de recherche en Infectiologie du CHU de Québec and Département de Microbiologie, Infectiologie et Immunologie, Université Laval, Québec City, Québec, Canada
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Marc Ouellette

* E-mail: marc.ouellette@crchul.ulaval.ca

Affiliation Centre de recherche en Infectiologie du CHU de Québec and Département de Microbiologie, Infectiologie et Immunologie, Université Laval, Québec City, Québec, Canada
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Leishmania
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Leishmania infantum
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Transfection
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Uracils
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Pyrimidines
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Point mutation
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Single nucleotide polymorphisms
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Genomics
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