Aerosol Exposure to Rift Valley Fever Virus Causes Earlier and More Severe Neuropathology in the Murine Model, which Has Important Implications for Therapeutic Development

Christopher Reed; Kenny Lin; Catherine Wilhelmsen; Brian Friedrich; Aysegul Nalca; Ashley Keeney; Ginger Donnelly; Joshua Shamblin; Lisa E. Hensley; Gene Olinger; Darci R. Smith

doi:10.1371/journal.pntd.0002156

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Open Access

Peer-reviewed

Research Article

Aerosol Exposure to Rift Valley Fever Virus Causes Earlier and More Severe Neuropathology in the Murine Model, which Has Important Implications for Therapeutic Development

Christopher Reed,

Affiliation United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, United States of America
⨯
Kenny Lin,

Affiliation United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, United States of America
⨯
Catherine Wilhelmsen,

Affiliation United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, United States of America
⨯
Brian Friedrich,

Affiliation United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, United States of America
⨯
Aysegul Nalca,

Affiliation United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, United States of America
⨯
Ashley Keeney,

Affiliation United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, United States of America
⨯
Ginger Donnelly,

Affiliation United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, United States of America
⨯
Joshua Shamblin,

Affiliation United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, United States of America
⨯
Lisa E. Hensley,

Current address: U.S. Food and Drug Administration, Silver Spring, Maryland, United States of America.

Affiliation United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, United States of America
⨯
Gene Olinger,

Affiliation United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, United States of America
⨯
Darci R. Smith

* E-mail: darci.smith@colostate.edu

Current address: Colorado State University, Fort Collins, Colorado, United States of America.

Affiliation United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland, United States of America
⨯

Aerosol Exposure to Rift Valley Fever Virus Causes Earlier and More Severe Neuropathology in the Murine Model, which Has Important Implications for Therapeutic Development

Christopher Reed,
Kenny Lin,
Catherine Wilhelmsen,
Brian Friedrich,
Aysegul Nalca,
Ashley Keeney,
Ginger Donnelly,
Joshua Shamblin,
Lisa E. Hensley,
Gene Olinger

Published: April 4, 2013
https://doi.org/10.1371/journal.pntd.0002156

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