Rapid and Scalable Plant-based Production of a Cholera Toxin B Subunit Variant to Aid in Mass Vaccination against Cholera Outbreaks

Krystal Teasley Hamorsky; J. Calvin Kouokam; Lauren J. Bennett; Keegan J. Baldauf; Hiroyuki Kajiura; Kazuhito Fujiyama; Nobuyuki Matoba

doi:10.1371/journal.pntd.0002046

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Open Access

Peer-reviewed

Research Article

Rapid and Scalable Plant-based Production of a Cholera Toxin B Subunit Variant to Aid in Mass Vaccination against Cholera Outbreaks

Krystal Teasley Hamorsky ,

Contributed equally to this work with: Krystal Teasley Hamorsky, J. Calvin Kouokam

Affiliations Owensboro Cancer Research Program, Owensboro, Kentucky, United States of America, Department of Pharmacology and Toxicology and James Graham Brown Cancer Center, University of Louisville School of Medicine, Louisville, Kentucky, United States of America
⨯
J. Calvin Kouokam ,

Contributed equally to this work with: Krystal Teasley Hamorsky, J. Calvin Kouokam

Affiliations Owensboro Cancer Research Program, Owensboro, Kentucky, United States of America, Department of Pharmacology and Toxicology and James Graham Brown Cancer Center, University of Louisville School of Medicine, Louisville, Kentucky, United States of America
⨯
Lauren J. Bennett,

Affiliation Owensboro Cancer Research Program, Owensboro, Kentucky, United States of America
⨯
Keegan J. Baldauf,

Affiliation Department of Pharmacology and Toxicology and James Graham Brown Cancer Center, University of Louisville School of Medicine, Louisville, Kentucky, United States of America
⨯
Hiroyuki Kajiura,

Affiliation International Center for Biotechnology, Osaka University, Osaka, Japan
⨯
Kazuhito Fujiyama,

Affiliation International Center for Biotechnology, Osaka University, Osaka, Japan
⨯
Nobuyuki Matoba

* E-mail: n.matoba@louisville.edu

Affiliations Owensboro Cancer Research Program, Owensboro, Kentucky, United States of America, Department of Pharmacology and Toxicology and James Graham Brown Cancer Center, University of Louisville School of Medicine, Louisville, Kentucky, United States of America
⨯

Rapid and Scalable Plant-based Production of a Cholera Toxin B Subunit Variant to Aid in Mass Vaccination against Cholera Outbreaks

Krystal Teasley Hamorsky,
J. Calvin Kouokam,
Lauren J. Bennett,
Keegan J. Baldauf,
Hiroyuki Kajiura,
Kazuhito Fujiyama,
Nobuyuki Matoba

Published: March 7, 2013
https://doi.org/10.1371/journal.pntd.0002046

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