First Discovery of Two Polyketide Synthase Genes for Mitorubrinic Acid and Mitorubrinol Yellow Pigment Biosynthesis and Implications in Virulence of Penicillium marneffei

Patrick C. Y. Woo; Ching-Wan Lam; Emily W. T. Tam; Chris K. F. Leung; Samson S. Y. Wong; Susanna K. P. Lau; Kwok-Yung Yuen

doi:10.1371/journal.pntd.0001871

Loading metrics

Open Access

Peer-reviewed

Research Article

First Discovery of Two Polyketide Synthase Genes for Mitorubrinic Acid and Mitorubrinol Yellow Pigment Biosynthesis and Implications in Virulence of Penicillium marneffei

Patrick C. Y. Woo ,

Contributed equally to this work with: Patrick C. Y. Woo, Ching-Wan Lam, Emily W. T. Tam

* E-mail: pcywoo@hkucc.hku.hk (PCYW); skplau@hkucc.hku.hk (SKPL)

Affiliations State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong, Department of Microbiology, The University of Hong Kong, Hong Kong
⨯
Ching-Wan Lam ,

Contributed equally to this work with: Patrick C. Y. Woo, Ching-Wan Lam, Emily W. T. Tam

Affiliation Department of Pathology, The University of Hong Kong, Hong Kong
⨯
Emily W. T. Tam ,

Contributed equally to this work with: Patrick C. Y. Woo, Ching-Wan Lam, Emily W. T. Tam

Affiliation State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong
⨯
Chris K. F. Leung,

Affiliation Department of Pathology, The University of Hong Kong, Hong Kong
⨯
Samson S. Y. Wong,

Affiliations State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong, Department of Microbiology, The University of Hong Kong, Hong Kong
⨯
Susanna K. P. Lau ,

* E-mail: pcywoo@hkucc.hku.hk (PCYW); skplau@hkucc.hku.hk (SKPL)

Affiliations State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong, Department of Microbiology, The University of Hong Kong, Hong Kong
⨯
Kwok-Yung Yuen

Affiliations State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong, Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong, Department of Microbiology, The University of Hong Kong, Hong Kong
⨯

First Discovery of Two Polyketide Synthase Genes for Mitorubrinic Acid and Mitorubrinol Yellow Pigment Biosynthesis and Implications in Virulence of Penicillium marneffei

Patrick C. Y. Woo,
Ching-Wan Lam,
Emily W. T. Tam,
Chris K. F. Leung,
Samson S. Y. Wong,
Susanna K. P. Lau,
Kwok-Yung Yuen

Published: October 18, 2012
https://doi.org/10.1371/journal.pntd.0001871

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Penicillium marneffei
Is the Subject Area "Penicillium marneffei" applicable to this article?

Thanks for your feedback.
Pigments
Is the Subject Area "Pigments" applicable to this article?

Thanks for your feedback.
Macrophages
Is the Subject Area "Macrophages" applicable to this article?

Thanks for your feedback.
Biosynthesis
Is the Subject Area "Biosynthesis" applicable to this article?

Thanks for your feedback.
Fungal genomics
Is the Subject Area "Fungal genomics" applicable to this article?

Thanks for your feedback.
Fungal genetics
Is the Subject Area "Fungal genetics" applicable to this article?

Thanks for your feedback.
Neutrophils
Is the Subject Area "Neutrophils" applicable to this article?

Thanks for your feedback.
Virulence factors
Is the Subject Area "Virulence factors" applicable to this article?

Thanks for your feedback.