Leishmania donovani Argininosuccinate Synthase Is an Active Enzyme Associated with Parasite Pathogenesis

• Ines Lakhal-Naouar,

  Affiliation Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), Bethesda, Maryland, United States of America

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• Armando Jardim,

  Affiliation Institute of Parasitology, McGill University and the Centre for Host-Parasite Interactions, Quebec, Canada

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• Rona Strasser,

  Affiliation Institute of Parasitology, McGill University and the Centre for Host-Parasite Interactions, Quebec, Canada

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• Shen Luo,

  Affiliation Laboratory of Chemistry, Division of Therapeutic Proteins, Center for Drug Evaluation and Research (CDER), Food and Drug Administration (FDA), Bethesda, Maryland, United States of America

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• Yukiko Kozakai,

  Affiliation Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), Bethesda, Maryland, United States of America

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• Hira L. Nakhasi,

  Affiliation Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), Bethesda, Maryland, United States of America

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• Robert C. Duncan

  * E-mail: robert.duncan@fda.hhs.gov

  Affiliation Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), Bethesda, Maryland, United States of America

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