Diverse Inhibitor Chemotypes Targeting Trypanosoma cruzi CYP51

• Shamila S. Gunatilleke ,

  Contributed equally to this work with: Shamila S. Gunatilleke, Claudia M. Calvet

  Affiliations Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

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• Claudia M. Calvet ,

  Contributed equally to this work with: Shamila S. Gunatilleke, Claudia M. Calvet

  Affiliations Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Cellular Ultra-Structure Laboratory, Oswaldo Cruz Institute (IOC), FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil

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• Jonathan B. Johnston,

  Affiliation Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America

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• Chiung-Kuang Chen,

  Affiliations Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America

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• Grigori Erenburg,

  Affiliation King's University College at the University of Western Ontario, London, Ontario, Canada

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• Jiri Gut,

  Affiliations Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

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• Juan C. Engel,

  Affiliations Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

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• Kenny K. H. Ang,

  Affiliation Small Molecule Discovery Center, University of California San Francisco, San Francisco, California, United States of America

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• Joseph Mulvaney,

  Affiliation Small Molecule Discovery Center, University of California San Francisco, San Francisco, California, United States of America

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• Steven Chen,

  Affiliation Small Molecule Discovery Center, University of California San Francisco, San Francisco, California, United States of America

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• Michelle R. Arkin,

  Affiliation Small Molecule Discovery Center, University of California San Francisco, San Francisco, California, United States of America

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• James H. McKerrow,

  Affiliations Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

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• Larissa M. Podust

  * E-mail: larissa.podust@ucsf.edu

  Affiliations Sandler Center for Drug Discovery, University of California San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

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