CD8 Cells of Patients with Diffuse Cutaneous Leishmaniasis Display Functional Exhaustion: The Latter Is Reversed, In Vitro, by TLR2 Agonists

Joselín Hernández-Ruiz; Norma Salaiza-Suazo; Georgina Carrada; Sofía Escoto; Adriana Ruiz-Remigio; Yvonne Rosenstein; Alejandro Zentella; Ingeborg Becker

doi:10.1371/journal.pntd.0000871

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Peer-reviewed

Research Article

CD8 Cells of Patients with Diffuse Cutaneous Leishmaniasis Display Functional Exhaustion: The Latter Is Reversed, In Vitro, by TLR2 Agonists

Joselín Hernández-Ruiz,

Affiliations Departamento de Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México, Hospital General de México OD, México Distrito Federal, Mexico, Dirección de Investigación, Hospital General de México OD, México Distrito Federal, Mexico
⨯
Norma Salaiza-Suazo,

Affiliation Departamento de Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México, Hospital General de México OD, México Distrito Federal, Mexico
⨯
Georgina Carrada,

Affiliation Secretaría de Salud del Estado de Tabasco y Universidad Juárez Autónoma de Tabasco, Villahermosa, Mexico
⨯
Sofía Escoto,

Affiliation Departamento de Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México, Hospital General de México OD, México Distrito Federal, Mexico
⨯
Adriana Ruiz-Remigio,

Affiliation Departamento de Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México, Hospital General de México OD, México Distrito Federal, Mexico
⨯
Yvonne Rosenstein,

Affiliation Instituto de Biotecnología y Posgrado en Ciencias Bioquímicas, Universidad Nacional Autónoma de México, Cuernavaca, Mexico
⨯
Alejandro Zentella,

Affiliations Departamento de Bioquímica, Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán”, Secretaría de Salud, México Distrito Federal, Mexico, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, México Distrito Federal, Mexico
⨯
Ingeborg Becker

* E-mail: becker@servidor.unam.mx

Affiliation Departamento de Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México, Hospital General de México OD, México Distrito Federal, Mexico
⨯

CD8 Cells of Patients with Diffuse Cutaneous Leishmaniasis Display Functional Exhaustion: The Latter Is Reversed, In Vitro, by TLR2 Agonists

Joselín Hernández-Ruiz,
Norma Salaiza-Suazo,
Georgina Carrada,
Sofía Escoto,
Adriana Ruiz-Remigio,
Yvonne Rosenstein,
Alejandro Zentella,
Ingeborg Becker

Published: November 2, 2010
https://doi.org/10.1371/journal.pntd.0000871

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