Macrofilaricidal Activity after Doxycycline Only Treatment of Onchocerca volvulus in an Area of Loa loa Co-Endemicity: A Randomized Controlled Trial

Joseph D. Turner; Nicholas Tendongfor; Mathias Esum; Kelly L. Johnston; R. Stuart Langley; Louise Ford; Brian Faragher; Sabine Specht; Sabine Mand; Achim Hoerauf; Peter Enyong; Samuel Wanji; Mark J. Taylor

doi:10.1371/journal.pntd.0000660

Loading metrics

Open Access

Peer-reviewed

Research Article

Macrofilaricidal Activity after Doxycycline Only Treatment of Onchocerca volvulus in an Area of Loa loa Co-Endemicity: A Randomized Controlled Trial

Joseph D. Turner,

Current address: Schistosome Research Group, Centre for Immunology and Infection, Department of Biology and Hull York Medical School, University of York, York, United Kingdom

Affiliation Filariasis Research Laboratory, Molecular and Biochemical Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
⨯
Nicholas Tendongfor,

Affiliations Department of Life Sciences, Faculty of Science, University of Buea, Buea, Cameroon, Research Foundation in Tropical Diseases and Environment (REFOTDE), Buea, Cameroon
⨯
Mathias Esum,

Affiliations Department of Life Sciences, Faculty of Science, University of Buea, Buea, Cameroon, Research Foundation in Tropical Diseases and Environment (REFOTDE), Buea, Cameroon
⨯
Kelly L. Johnston,

Affiliation Filariasis Research Laboratory, Molecular and Biochemical Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
⨯
R. Stuart Langley,

Affiliation Filariasis Research Laboratory, Molecular and Biochemical Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
⨯
Louise Ford,

Affiliation Filariasis Research Laboratory, Molecular and Biochemical Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
⨯
Brian Faragher,

Affiliation Filariasis Research Laboratory, Molecular and Biochemical Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
⨯
Sabine Specht,

Affiliation Institute of Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn, Bonn, Germany
⨯
Sabine Mand,

Affiliation Institute of Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn, Bonn, Germany
⨯
Achim Hoerauf,

Affiliation Institute of Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn, Bonn, Germany
⨯
Peter Enyong,

Affiliation Tropical Medicine Research Station, Kumba, Cameroon
⨯
Samuel Wanji,

Affiliations Department of Life Sciences, Faculty of Science, University of Buea, Buea, Cameroon, Research Foundation in Tropical Diseases and Environment (REFOTDE), Buea, Cameroon
⨯
Mark J. Taylor

* E-mail: mark.taylor@liverpool.ac.uk

Affiliation Filariasis Research Laboratory, Molecular and Biochemical Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
⨯

Macrofilaricidal Activity after Doxycycline Only Treatment of Onchocerca volvulus in an Area of Loa loa Co-Endemicity: A Randomized Controlled Trial

Joseph D. Turner,
Nicholas Tendongfor,
Mathias Esum,
Kelly L. Johnston,
R. Stuart Langley,
Louise Ford,
Brian Faragher,
Sabine Specht,
Sabine Mand,
Achim Hoerauf

Published: April 13, 2010
https://doi.org/10.1371/journal.pntd.0000660

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Doxycycline
Is the Subject Area "Doxycycline" applicable to this article?

Thanks for your feedback.
Onchocerca volvulus
Is the Subject Area "Onchocerca volvulus" applicable to this article?

Thanks for your feedback.
Loa loa
Is the Subject Area "Loa loa" applicable to this article?

Thanks for your feedback.
Onchocerciasis
Is the Subject Area "Onchocerciasis" applicable to this article?

Thanks for your feedback.
Wolbachia
Is the Subject Area "Wolbachia" applicable to this article?

Thanks for your feedback.
Adverse events
Is the Subject Area "Adverse events" applicable to this article?

Thanks for your feedback.
Adverse reactions
Is the Subject Area "Adverse reactions" applicable to this article?

Thanks for your feedback.
Drug therapy
Is the Subject Area "Drug therapy" applicable to this article?

Thanks for your feedback.