Leishmania major Glycosylation Mutants Require Phosphoglycans (lpg2−) but Not Lipophosphoglycan (lpg1−) for Survival in Permissive Sand Fly Vectors

Open Access

Peer-reviewed

Research Article

Leishmania major Glycosylation Mutants Require Phosphoglycans (lpg2⁻) but Not Lipophosphoglycan (lpg1⁻) for Survival in Permissive Sand Fly Vectors

Anna Svárovská,

Affiliation Department of Parasitology, Faculty of Science, Charles University in Prague, Czech Republic
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Thomas H. Ant,

Affiliation Keele University, Keele, Staffordshire, United Kingdom
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Veronika Seblová,

Affiliation Department of Parasitology, Faculty of Science, Charles University in Prague, Czech Republic
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Lucie Jecná,

Affiliation Department of Parasitology, Faculty of Science, Charles University in Prague, Czech Republic
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Stephen M. Beverley,

Affiliation Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Petr Volf

* E-mail: volf@cesnet.cz

Affiliation Department of Parasitology, Faculty of Science, Charles University in Prague, Czech Republic
⨯

Parasitic diseases
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Sand flies
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Leishmania
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Lectins
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Serine proteases
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Leishmania infantum
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Phlebotomus
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Leishmania major
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