NMR Analysis of the Dynamic Exchange of the NS2B Cofactor between Open and Closed Conformations of the West Nile Virus NS2B-NS3 Protease

Open Access

Peer-reviewed

Research Article

Xun-Cheng Su ,

Contributed equally to this work with: Xun-Cheng Su, Kiyoshi Ozawa

Affiliation Australian National University, Research School of Chemistry, Canberra, Australia
⨯
Kiyoshi Ozawa ,

Contributed equally to this work with: Xun-Cheng Su, Kiyoshi Ozawa

Affiliation Australian National University, Research School of Chemistry, Canberra, Australia
⨯
Ruhu Qi,

Affiliation Australian National University, Research School of Chemistry, Canberra, Australia
⨯
Subhash G. Vasudevan,

Current address: Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, 8 College Road, Singapore 169857

Affiliation Novartis Institute for Tropical Diseases, Chromos, Singapore
⨯
Siew P. Lim,

Affiliation Novartis Institute for Tropical Diseases, Chromos, Singapore
⨯
Gottfried Otting

* E-mail: go@rsc.anu.edu.au

Affiliation Australian National University, Research School of Chemistry, Canberra, Australia
⨯

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Proteases
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West Nile virus
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Dengue virus
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Crystal structure
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Cell membranes
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NMR spectroscopy
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Isoleucine
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Host cells
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