Deletion of Fibrinogen-like Protein 2 (FGL-2), a Novel CD4⁺ CD25⁺ Treg Effector Molecule, Leads to Improved Control of Echinococcus multilocularis Infection in Mice

• Junhua Wang,

  Affiliations Institute of Parasitology, University of Bern, Bern, Switzerland, State Key Lab Incubation Base of Xinjiang Major Diseases Research (2010DS890294) and Xinjiang Key Laboratory of Echinococcosis, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China, Department of Nuclear Medicine, University of Franche-Comté and Jean Minjoz University Hospital, Besançon, Franche-Comté, France

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• Dominique A. Vuitton,

  Affiliation World Health Organization (WHO)-Collaborating Centre for the Prevention and Treatment of Human Echinococcosis, University of Franche-Comté and University Hospital, Besançon, Franche-Comté, France

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• Norbert Müller,

  Affiliation Institute of Parasitology, University of Bern, Bern, Switzerland

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• Andrew Hemphill,

  Affiliation Institute of Parasitology, University of Bern, Bern, Switzerland

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• Markus Spiliotis,

  Affiliation Institute of Parasitology, University of Bern, Bern, Switzerland

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• Oleg Blagosklonov,

  Affiliation Department of Nuclear Medicine, University of Franche-Comté and Jean Minjoz University Hospital, Besançon, Franche-Comté, France

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• Denis Grandgirard,

  Affiliation Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Bern, Switzerland

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• Stephen L. Leib,

  Affiliations Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Bern, Switzerland, Biology Division, Spiez Laboratory, Federal Office for Civil Protection (FOCP), Spiez, Switzerland

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• Itay Shalev,

  Affiliation University of Toronto Transplantation Institute, Toronto, Ontario, Canada

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• Gary Levy,

  Affiliation University of Toronto Transplantation Institute, Toronto, Ontario, Canada

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• Xiaomei Lu,

  Affiliation State Key Lab Incubation Base of Xinjiang Major Diseases Research (2010DS890294) and Xinjiang Key Laboratory of Echinococcosis, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China

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• Renyong Lin,

  Affiliation State Key Lab Incubation Base of Xinjiang Major Diseases Research (2010DS890294) and Xinjiang Key Laboratory of Echinococcosis, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China

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• Hao Wen,

  Affiliation State Key Lab Incubation Base of Xinjiang Major Diseases Research (2010DS890294) and Xinjiang Key Laboratory of Echinococcosis, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China

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• Bruno Gottstein

  * E-mail: bruno.gottstein@vetsuisse.unibe.ch

  Affiliation Institute of Parasitology, University of Bern, Bern, Switzerland

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