Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental models

Grace Zdesenko; Francisca Mutapi

doi:10.1371/journal.pntd.0008649

Loading metrics

Open Access

Review articles summarize the best available evidence on a topic relevant to the NTD community.

See all article types »

Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental models

Grace Zdesenko ,

* E-mail: g.zdesenko@sms.ed.ac.uk

Affiliations Institute of Immunology & Infection Research, University of Edinburgh, Ashworth Laboratories, King’s Buildings, Edinburgh, United Kingdom, NIHR Global Health Research Unit Tackling Infections to Benefit Africa (TIBA), University of Edinburgh, Ashworth Laboratories, King’s Buildings, Edinburgh, United Kingdom

http://orcid.org/0000-0002-0012-3436

⨯
Francisca Mutapi

Affiliations Institute of Immunology & Infection Research, University of Edinburgh, Ashworth Laboratories, King’s Buildings, Edinburgh, United Kingdom, NIHR Global Health Research Unit Tackling Infections to Benefit Africa (TIBA), University of Edinburgh, Ashworth Laboratories, King’s Buildings, Edinburgh, United Kingdom
⨯

Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental models

Grace Zdesenko,
Francisca Mutapi

Published: September 25, 2020
https://doi.org/10.1371/journal.pntd.0008649

About the Authors

Grace Zdesenko

* E-mail: g.zdesenko@sms.ed.ac.uk

Affiliations Institute of Immunology & Infection Research, University of Edinburgh, Ashworth Laboratories, King’s Buildings, Edinburgh, United Kingdom, NIHR Global Health Research Unit Tackling Infections to Benefit Africa (TIBA), University of Edinburgh, Ashworth Laboratories, King’s Buildings, Edinburgh, United Kingdom

http://orcid.org/0000-0002-0012-3436

Francisca Mutapi

Competing Interests

The authors have declared that no competing interests exist.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Drug metabolism
Is the Subject Area "Drug metabolism" applicable to this article?

Thanks for your feedback.
Enantiomers
Is the Subject Area "Enantiomers" applicable to this article?

Thanks for your feedback.
Enzyme metabolism
Is the Subject Area "Enzyme metabolism" applicable to this article?

Thanks for your feedback.
Drug therapy
Is the Subject Area "Drug therapy" applicable to this article?

Thanks for your feedback.
Metabolic pathways
Is the Subject Area "Metabolic pathways" applicable to this article?

Thanks for your feedback.
Schistosomiasis
Is the Subject Area "Schistosomiasis" applicable to this article?

Thanks for your feedback.
Metabolites
Is the Subject Area "Metabolites" applicable to this article?

Thanks for your feedback.
Drug interactions
Is the Subject Area "Drug interactions" applicable to this article?

Thanks for your feedback.