About the Authors

Manu De Rycker

m.derycker@dundee.ac.uk (MDR); d.w.gray@dundee.ac.uk (DWG)

Affiliation Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee, United Kingdom

John Thomas

Affiliation Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee, United Kingdom

Jennifer Riley

Affiliation Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee, United Kingdom

Stephen J. Brough

Affiliation GlaxoSmithKline, Biological Sciences, Medicines Research Centre, Stevenage, Hertfordshire, United Kingdom

Tim J. Miles

Affiliation GlaxoSmithKline, Diseases of the Developing World, Parque Tecnologico de Madrid, Servero Ochoa, Madrid, Spain

David W. Gray

m.derycker@dundee.ac.uk (MDR); d.w.gray@dundee.ac.uk (DWG)

Affiliation Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee, United Kingdom

Competing Interests

TM and SB are employed by GlaxoSmithKline. MDR, JT, JR and DWG have no competing interests to declare.

Author Contributions

Conceived and designed the experiments: MDR JT JR SJB TJM DWG. Performed the experiments: MDR JT JR SJB. Analyzed the data: MDR JT JR SJB TJM DWG. Wrote the paper: MDR TJM DWG.