About the Authors
- Thavy Long
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* E-mail: tlong@ucsd.edu (TL); (ccaffrey@ucsd.edu) (CRC)
Current address: Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, United States of America
Affiliations Center for Discovery and Innovation in Parasitic Diseases, University of California, San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California, San Francisco, San Francisco, California, United States of America
- R. Jeffrey Neitz
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Affiliations Center for Discovery and Innovation in Parasitic Diseases, University of California, San Francisco, San Francisco, California, United States of America, Small Molecule Discovery Center, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America
- Rachel Beasley
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Affiliation Department of Computer Science, San Francisco State University, San Francisco, California, United States of America
- Chakrapani Kalyanaraman
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Affiliation Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America
- Brian M. Suzuki
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Current address: Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, United States of America
Affiliations Center for Discovery and Innovation in Parasitic Diseases, University of California, San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California, San Francisco, San Francisco, California, United States of America
- Matthew P. Jacobson
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Affiliation Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America
- Colette Dissous
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Affiliation Center of Infection and Immunity of Lille, Université Lille Nord de France, Inserm U1019, CNRS-UMR 8204, Institut Pasteur de Lille, Lille, France
- James H. McKerrow
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Current address: Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, United States of America
Affiliations Center for Discovery and Innovation in Parasitic Diseases, University of California, San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California, San Francisco, San Francisco, California, United States of America
- David H. Drewry
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Affiliation Department of Chemical Biology, GlaxoSmithKline, Research Triangle Park, North Carolina, United States of America
- William J. Zuercher
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Affiliation Department of Chemical Biology, GlaxoSmithKline, Research Triangle Park, North Carolina, United States of America
- Rahul Singh
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Affiliations Center for Discovery and Innovation in Parasitic Diseases, University of California, San Francisco, San Francisco, California, United States of America, Department of Computer Science, San Francisco State University, San Francisco, California, United States of America
- Conor R. Caffrey
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* E-mail: tlong@ucsd.edu (TL); (ccaffrey@ucsd.edu) (CRC)
Current address: Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, United States of America
Affiliations Center for Discovery and Innovation in Parasitic Diseases, University of California, San Francisco, San Francisco, California, United States of America, Department of Pathology, University of California, San Francisco, San Francisco, California, United States of America
Competing Interests
The authors have declared that no competing interests exist. DHD and WJZ were employed by GlaxoSmithKline until April 2015. They are no longer working in this company. This does not alter our adherence to all PLOS policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: TL CK MPJ RS CRC. Performed the experiments: TL RB CK BMS RS CRC. Analyzed the data: TL RJN RB CK MPJ DHD WJZ RS CRC. Contributed reagents/materials/analysis tools: CK MPJ CD JHM DHD WJZ RS. Wrote the paper: TL RJN CK MPJ CD JHM DHD WJZ RS CRC.