Evidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma mansoni

Swarna Bais; Matthew A. Churgin; Christopher Fang-Yen; Robert M. Greenberg

doi:10.1371/journal.pntd.0004295

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Open Access

Peer-reviewed

Research Article

Evidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma mansoni

Swarna Bais,

Affiliation Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Matthew A. Churgin,

Affiliation Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Christopher Fang-Yen,

Affiliation Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Robert M. Greenberg

* E-mail: rgree@vet.upenn.edu

Affiliation Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯

Evidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma mansoni

Swarna Bais,
Matthew A. Churgin,
Christopher Fang-Yen,
Robert M. Greenberg

Published: December 11, 2015
https://doi.org/10.1371/journal.pntd.0004295

About the Authors

Swarna Bais

Affiliation Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Matthew A. Churgin

Affiliation Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Christopher Fang-Yen

Affiliation Department of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Robert M. Greenberg

* E-mail: rgree@vet.upenn.edu

Affiliation Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RMG SB. Performed the experiments: SB RMG. Analyzed the data: SB RMG. Contributed reagents/materials/analysis tools: MAC CFY. Wrote the paper: RMG SB MAC CFY.

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Transient receptor potential channels
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Schistosoma
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Schistosoma mansoni
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Small interfering RNA
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Serotonin
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Ion channels
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Gene prediction
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Genomic databases
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